Valance Od 500 Mg Tablet Pr 15

Valance Od 500 Tablet Pr 15

Abbott Healthcare Pvt. Ltd

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MRP ~~₹370.72~~

₹303.99

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Composition

Divalproex (500 Mg)

Strength:

500 MG 250 MG 750 MG 1000 MG

Valance OD 500 Tablet is primarily used to manage epilepsy and seizure disorders. This medicine falls in the category of anticonvulsants a group of medicines designed to control and prevent seizures.

In addition to epilepsy, this medicine is also used in the management of manic episodes linked with bipolar disorder and as a prophylaxis for migraine headaches. These additional uses help make this medicine versatile and beneficial for patients dealing with these neurological conditions.

Before you start taking this medicine, it's imperative to consult your doctor for appropriate dosage and frequency instructions. It's also essential to inform your doctor about any pre-existing conditions or ongoing medications that you might have. If you experience any side effects while on this medicine, ensure to notify your doctor immediately. Always remember to continue taking the medicine for the duration prescribed by your doctor for the best results.

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Valance OD 500 Tablet is used for the following:

Managing epilepsy and seizure disorders
Controlling manic episodes linked with bipolar disorder
Preventing migraine headaches

Directions for Use of Valance Od 500 Tablet Pr 15

Follow these steps while taking Valance OD 500 Tablet:

The tablet should be swallowed whole with a glass of water. This means you should not crush or chew it.
The medicine must not be stopped without consulting your doctor first. If you have any doubts or questions about how to take this medicine correctly, your doctor will be able to help.

Valance OD 500 Tablet is taken orally.

Side Effects of Valance Od 500 Tablet Pr 15

Valance OD 500 Tablet may have the following common side effects:

Nausea
Vomiting
Abdominal pain
Diarrhoea
Dizziness and drowsiness
Tremors: This means involuntary shaky movements that you may experience in your hands, arms, or legs.
Hair loss
Weight gain

Managing the Side Effects:

Most side effects are temporary and generally harmless, which resolve on discontinuing the use of Valance OD 500 Tablet. However, if you experience any serious side effects or worsening of any of the symptoms, please consult your doctor.

Here are some general guidelines for managing common side effects:

Nausea/Vomiting: Try taking Valance OD 500 Tablet with food or milk to reduce these effects.
Abdominal pain: If you experience stomach discomfort, consider taking this medicine after meals.

Valance OD 500 Tablet contains divalproex (500 mg), which operates in your body as follows:

Increases GABA Levels: Divalproex boosts the levels of gamma-aminobutyric acid (GABA), a substance that blocks signals in the brain. This helps in calming the nervous system and reducing seizures.
Stabilizes Electrical Activity: By increasing GABA levels, Divalproex aids in stabilising abnormal electrical activity in the brain. This plays a vital role in managing manic episodes and preventing migraine headaches.

Pregnancy

Valance OD 500 Tablet is contraindicated during pregnancy due to the risk of neural tube defects and other congenital malformations. If you are pregnant or planning a pregnancy, discuss this with your doctor before starting this medicine.

Breastfeeding

Caution is advised while breastfeeding when taking Valance OD 500 Tablet. Discuss potential risks and benefits with your doctor.

Alcohol

Avoid alcohol consumption while taking Valance OD 500 Tablet as it may increase the risk of side effects.

Liver

This medicine should be used with caution if you have liver disease or impairment. Discuss this with your doctor, as Valance OD 500 Tablet may affect liver function.

Kidney

If you have a history of kidney problems, it is a good idea to consult your doctor before taking Valance OD 500 Tablet.

Using Machines & Driving

You might experience drowsiness or dizziness while taking Valance OD 500 Tablet. Avoid driving or operating heavy machinery until you are sure how this medicine affects you.

Allergy

If you have a known hypersensitivity to Divalproex or any other components of Valance OD 500 Tablet, avoid using this medicine.

Children

Caution is advised when giving Valance OD 500 Tablet to children under 18 years of age. Always consult your doctor before giving any medicine to a child.

Older Patients

Older patients should take Valance OD 500 Tablet under medical supervision as they may be more susceptible to its side effects. Caution is advised if patients are above 70 years old. Your doctor will guide you based on your health status.

Interactions of Valance Od 500 Tablet Pr 15

Drug-Drug Interactions

Valance OD 500 Tablet interacts with the following medicines:

Salicylates: Aspirin and other salicylates can elevate the risk of bleeding when taken with Valance OD 500 Tablet.
Carbapenem Antibiotics: Medicines like Meropenem or Imipenem can decrease levels of Valance OD 500 Tablet in your body.
Hormonal Contraceptives: Estrogen-containing contraceptives, such as Norethisterone, might have reduced efficacy when used alongside this medicine.
Certain Epilepsy Medications: Lamotrigine levels could increase when used with this tablet, elevating the risk of potential toxicity.

Drug-Food Interactions

There are no known food interactions with Valance OD 500 Tablet.

Drug-Disease Interactions

Valance OD 500 Tablet interacts with the following diseases:

Liver Disease: If you have liver disease or impairment, this medication could exacerbate your condition.
Pancreatic Disorders: Individuals suffering from pancreatic disorders should use this medication cautiously as it could worsen their symptoms.
Urea Cycle Disorders: This medicine should be used carefully if you have urea cycle disorders as it may increase blood ammonia levels.
Mitochondrial Disorders: If you're diagnosed with Alpers-Huttenlocher syndrome or other mitochondrial disorders, you should exercise caution while taking this medicine.

Daily Dose

The daily dose of Valance OD 500 Tablet should be taken as instructed by your doctor. Your dosage may vary depending on things like how severe your condition is and how well you respond to the medicine. Remember to always stick to the dose prescribed by your doctor.

Over Dose

If you accidentally take more than the prescribed dose of Valance OD 500 Tablet, you may feel extremely tired or drowsy. In such a case, inform your doctor about it.

Missed Dose

If you forget to take Valance OD 500 Tablet, take it as soon as you remember. If it's nearly time for your next dose, skip the one you missed and go back to your regular schedule. Always consult your doctor before changing your dosage.

Store Valance OD 500 Tablet at room temperature, below 30°C.
Keep it in a dry place, shielded from light and dampness.
Maintain the tablet in its original packaging until it's time to take it.
Keep this medicine out of the reach of children.
Always check the expiry date before using Valance OD 500 Tablet.

If you experience seizures, try to avoid potential triggers. These could include things like flashing lights, lack of sleep, or stress. Regular exercise might help reduce stress and improve your overall health.
For managing bipolar disorder, maintaining a regular sleep schedule is crucial. Avoid excessive caffeine and alcohol that can disrupt your sleeping patterns. Seek help if you struggle to get enough rest.

Fact Box

Drug Category	GABA Enhancer
Therapeutic Category	Antiepileptic
Available Dosage Types	Tablet
Habit Forming	No
Ailment	Epilepsy, Bipolar disorder, Migraine prophylaxis

What is Valance OD 500 Tablet used for?

Valance OD 500 Tablet is primarily used to manage epilepsy, manic episodes in bipolar disorder, and to prevent migraine headaches.

How does Valance OD 500 Tablet work?

The medicine works by increasing levels of a calming chemical in the brain, which helps to stabilise abnormal electrical activity and reduce seizures, manic episodes, and migraines.

Should I take Valance OD 500 Tablet with food?

You can take the medicine with or without food. However, it's important not to chew, crush or divide the tablets; swallow them whole.

What are some common side effects of Valance OD 500 Tablet?

Common side effects can include nausea, diarrhoea, dizziness, tremors, hair loss and weight gain. If you notice any severe reactions, consult your doctor immediately.

Can Valance OD 500 Tablet interact with other medications?

Yes, it can interact with various medications including aspirin, antibiotics like carbapenems, hormonal contraceptives and others. Always inform your doctor about any other medicines you're taking.

What precautions should I take while using Valance OD 500 Tablet?

Use this medicine cautiously if you have liver disease, pancreatic disorders or bleeding disorders. It's contraindicated in pregnant women due to risk of birth defects.

What should I do in case of an overdose?

If you suspect an overdose of Valance OD 500 Tablet, seek immediate medical attention. Symptoms may include extreme lethargy or coma, respiratory difficulties and low blood pressure.

Last Updated On 23 Dec. 2024 | 10:53AM (IST)

Certified Content

Written by

Dr Nikita Lobo

Medical Editor & Reviewer | 7 years

BDS, MDS

Reviewed by

Dr. Chhavi Rosha

Health & Medical Content Writer | 8 years

BMS, FMC, MD Resident

Check out Editorial Policy

Manufacturer details

3 Corporate Park , Sion-Trombay Road , Chembur, Mumbai 400 071 India

Country of origin: INDIA

References

FDA. (2011). Depakote (divalproex sodium) Tablets for Oral use (pp. 1–57). https://www.accessdata.fda.gov/drugsatfda_docs/label/2011/018723s037lbl.pdf
HIGHLIGHTS OF PRESCRIBING INFORMATION. (2023). [Prescribing information]. https://www.accessdata.fda.gov/drugsatfda_docs/label/2023/021168s044lbl.pdf
DailyMed - DIVALPROEX SODIUM capsule, coated pellets. (n.d.). https://dailymed.nlm.nih.gov/dailymed/lookup.cfm?setid=71e803ef-f684-dc73-9612-9c05cb091405&version=7
Divalproex sodium | DrugBank Online. (n.d.). DrugBank. https://go.drugbank.com/salts/DBSALT000185
Bond, D. J., Lam, R. W., & Yatham, L. N. (2010). Divalproex sodium versus placebo in the treatment of acute bipolar depression: A systematic review and meta-analysis. Journal of Affective Disorders, 124(3), 228–234. https://doi.org/10.1016/j.jad.2009.11.008

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