Valparin 200 Tablet 15

Sanofi India Ltd.

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Composition

Sodium Valproate / Valproic Acid (200 Mg)

Strength:

500 MG 200 MG

Valparin 200 Alkalets Tablet is used to treat conditions like bipolar disorder, epilepsy, and migraines. It works by increasing a natural chemical in the brain, which helps calm nerve activity, reducing symptoms like mood swings and seizures. It’s also helpful for managing trigeminal neuralgia.

It's vital to consult your doctor for the appropriate dosage and frequency based on your specific condition. Before starting this medication, inform your doctor about any pre-existing conditions or ongoing medications. Any side effects should be promptly reported to your doctor. It's crucial to continue taking the medicine for the duration prescribed by your doctor for optimal results.

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Valparin 200 Alkalets Tablet is used to manage epilepsy, bipolar disorder (manic phase), and prevent migraines by reducing their frequency and severity.

Directions for Use of Valparin 200 Tablet 15

Follow the dosage and timing instructions provided by your doctor precisely.
Do not change or exceed the prescribed dose without consulting your doctor.
Consult your doctor before discontinuing the medication; do not stop taking it without their guidance.
Adhere to the dietary recommendations given by your doctor.

Valparin 200 Alkalets Tablet is taken orally.

Valparin 200 Alkalets Tablet may have the following common side effects:

Nausea
Vomiting
Diarrhoea
Abdominal pain
Dizziness
Drowsiness
Fatigue
Headache
Tremors
Difficulty walking straight
Blurred or double vision
Hair loss
Weight gain
Irregular menstrual periods

Managing the Side Effects:

Most side effects are temporary and generally harmless, which resolve on discontinuing the use of Valparin 200 Alkalets Tablet. However, if you experience any serious side effects or worsening of any of the symptoms, please consult your doctor. Here are some general guidelines for managing common side effects:

Nausea or Vomiting: Follow the dietary recommendations provided by your doctor.
Dizziness or Drowsiness: Avoid activities your doctor has advised against and follow their recommendations.

Valparin 200 Alkalets Tablet contains sodium valproate (200 mg) and works on the body in the following ways:

Increases GABA Levels: Sodium valproate increases the levels of a neurotransmitter called GABA (gamma-aminobutyric acid) in the brain. Neurotransmitters are chemicals that send signals between nerve cells. GABA has a calming effect on brain activity, which helps control seizures and stabilize mood.
Reduces Overactivity: It reduces excessive firing and excitation of nerve cells in the brain, thereby helping to control seizures.
Modulates Other Pathways: Sodium valproate also modulates other neurotransmitters and pathways involved in migraine pathogenesis, helping reduce the frequency and severity of migraines.

Pregnancy

Valparin 200 Alkalets Tablet should not be used during pregnancy, especially for migraine prevention, as it can cause birth defects. If you are pregnant or planning to conceive, discuss this with your doctor before starting this medicine.

Breastfeeding

This medicine passes into breast milk and may cause side effects in a nursing infant. It's advisable to consult your doctor before breastfeeding while taking Valparin 200 Alkalets Tablet.

Alcohol

Limiting alcohol intake is recommended while taking this medicine, as it may worsen side effects like drowsiness and potentially harm the liver.

Liver

Caution is important when taking Valparin 200 Alkalets Tablet if you have mild to moderate liver impairment. This medicine is not recommended for those with severe liver diseases or significant liver dysfunction. Discuss your liver health with your doctor before starting this medication.

Kidney

If you have a history of kidney problems, it's advisable to consult your doctor before taking Valparin 200 Alkalets Tablet.

Using Machines & Driving

Valparin 200 Alkalets Tablet may cause drowsiness and dizziness. Be careful when driving or operating machinery until you know how this medicine affects you.

Allergy

This medicine is contraindicated if you have known hypersensitivity to sodium valproate or any of the tablet's inactive ingredients. If you have any allergies, discuss them with your doctor before beginning this medication.

Children

Valparin 200 Alkalets Tablet can cause serious liver damage, particularly in children under two years of age and those with certain metabolic disorders. Always consult your doctor before giving this medicine to a child.

Older Patients

Older patients should take Valparin 200 Alkalets Tablet under medical supervision as they may be more susceptible to its side effects. Caution is advised if patients are above 70 years of age. Your doctor will guide you based on your health status.

Drug-Drug Interactions

Valparin 200 Alkalets Tablet interacts with the following medicines:

Blood clotting medications: When combined with aspirin or warfarin, Valparin 200 Alkalets Tablet may alter blood clotting and increase the risk of bleeding.
Antibiotics: Certain antibiotics like imipenem and meropenem may decrease the effectiveness of the Valparin 200 Alkalets Tablet when used together.
Seizure medications: Other seizure medications such as lamotrigine, phenytoin, and carbamazepine might interact with this medicine, potentially altering its effects.
Antidepressants and antipsychotics: These may enhance the side effects of Valparin 200 Alkalets Tablet, like drowsiness and dizziness.
Medications affecting blood levels: Cimetidine, erythromycin, and rifampin may affect valproate blood levels and hence alter its effect.
Oral contraceptives: The effectiveness of these medicines may be reduced when taken with Valparin 200 Alkalets Tablet.

Drug-Food Interactions

There is no specific food interaction with this medicine.

Drug-Disease Interactions

Valparin 200 Alkalets Tablet interacts with the following diseases:

Liver disease: Those with liver disease or significant dysfunction should be cautious as this medicine could worsen their condition.
Urea cycle disorders: Known urea cycle disorders could be affected by this medicine.
Diabetes: Valparin 200 Alkalets Tablet could interfere with blood sugar control making diabetes management challenging.

Daily Dose

The daily dose of Valparin 200 Alkalets Tablet should be as advised by your doctor. The dosage may vary depending on factors like the severity of your condition and how you respond to the medicine. Always stick to the prescribed dosage and never alter it without consulting your doctor.

Over Dose

If you accidentally take more Valparin 200 Alkalets Tablet than recommended, you might experience severe drowsiness or weakness. If these or any other unusual symptoms persist, please inform your doctor.

Missed Dose

If you forget to take your Valparin 200 Alkalets Tablet, take it as soon as you remember. However, if it's nearly time for your next dose, skip the missed dose and resume your usual schedule. Never double up your dose without consulting your doctor.

Store the Valparin 200 Alkalets Tablet at room temperature, not exceeding 30 degrees Celsius.
Choose a dry, cool spot that is not directly exposed to sunlight or heat.
Keep the medicine securely closed in its original packaging to protect it from moisture and air.
Always keep this medicine out of reach of children.
Make sure you use the tablet before its expiry date.

If you are taking Valparin 200 Alkalets Tablet for epilepsy or bipolar disorder, try to maintain a regular sleep pattern. Irregular sleep can potentially increase the frequency of seizures or cause mood swings.
If using this medicine for migraine prevention, it may help to limit your intake of caffeine and chocolate. These foods are known triggers for migraines in some people. Always consult your doctor for personalised advice.

Fact Box

Drug Category	GABA Enhancer
Therapeutic Category	Anticonvulsant
Available Dosage Types	Tablet
Habit Forming	No
Ailment	Epilepsy, Bipolar Disorder, Migraine

What is Valparin 200 Alkalets Tablet used for?

It's used to manage epilepsy, bipolar disorder, and reduce the frequency of migraine headaches.

How does Valparin 200 Alkalets Tablet work?

It increases calming neurotransmitters in the brain, reducing excessive nerve cell activity and modulating other pathways involved in migraines.

How should I take Valparin 200 Alkalets Tablet?

You must take the medicine exactly as prescribed by your doctor.

Can I stop Valparin 200 Alkalets Tablet suddenly?

No, stopping abruptly may worsen your condition. Always consult your doctor for guidance when discontinuing the medication.

What precautions should I take while using Valparin 200 Alkalets Tablet?

Inform your doctor about any medical conditions you have, limit alcohol intake, and avoid driving or operating machinery until you know its effects.

Are there any side effects of Valparin 200 Alkalets Tablet?

Yes, common side effects include nausea, dizziness, tremor, hair loss and weight gain. Seek immediate medical attention for serious side effects.

Can I use Valparin 200 Alkalets Tablet during pregnancy or while breastfeeding?

This medicine can cause birth defects and may pass into breast milk. Always discuss risks and benefits with your doctor first.

Last Updated On 29 Jan. 2025 | 4:11PM (IST)

Certified Content

Written by

Dr. Michelle Frank

Medical Content Writer | 9 years

Doctor of Medicine

Reviewed by

Dr. Meenakshi Maruwada

Medical Content Writer & Strategist | 8 years

BDS, PGCAD, GMHE (IIM-B)

Check out Editorial Policy

Manufacturer details

CTS No.117-B L & T Business Park, Saki Vihar Rd, Powai, Mumbai, Maharashtra 400072

Country of origin: INDIA

References

NHS UK. (n.d.). Valproic acid: a medicine to treat epilepsy and bipolar disorder. Retrieved 1 April 2024, from https://www.nhs.uk/medicines/valproic-acid/
U.S. Food and Drug Administration. (2020). [Package insert for Valproic Acid]. Retrieved 1 April 2024, from https://www.accessdata.fda.gov/drugsatfda_docs/label/2024/212839s008lbl.pdf
Valproic acid: MedlinePlus drug information. (n.d.). https://medlineplus.gov/druginfo/meds/a682412.html
Valproic acid: Uses, Interactions, Mechanism of Action | DrugBank Online. (n.d.). DrugBank. https://go.drugbank.com/drugs/DB00313
Rahman, M., Awosika, A. O., & Nguyen, H. (2024, March 19). Valproic acid. StatPearls - NCBI Bookshelf. https://www.ncbi.nlm.nih.gov/books/NBK559112/

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