Valparin Chrono 300 Mg Tablet Cr 15

Valparin Chrono 300 Tablet 15

Sanofi India Ltd.

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Composition

Sodium Valproate / Valproic Acid (300 Mg)

Strength:

300 MG 500 MG 200 MG

Valparin Chrono 300 Tablet is primarily used to manage epilepsy, a neurological disorder marked by recurrent seizures. This medication is an anticonvulsant, which belongs to a group of medicines specifically designed to control seizures.

Apart from epilepsy, this medicine also helps in managing bipolar disorder by controlling mood swings. Additionally, it assists in the prevention of migraine headaches when taken regularly, thereby reducing the frequency and severity of these debilitating episodes.

Before starting on this medication, you should consult your doctor who will guide you on the appropriate dosage and frequency. It is essential to inform your doctor about any existing health conditions or current medications you are on. If you experience any side effects while taking this medicine, notify your doctor promptly. Also, ensure that you continue taking the medicine for the duration prescribed by your doctor for optimal benefits.

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Valparin Chrono 300 Tablet is used for the following:

Management of epilepsy: Generalised tonic-clonic seizures, absence seizures, myoclonic seizures, and partial seizures
Control of manic episodes in bipolar disorder

Directions for Use of Valparin Chrono 300 Tablet 15

To use Valparin Chrono 300 Tablet correctly, follow these steps:

Follow the precise dosage and timing instructions provided by your doctor.
Do not change or exceed the prescribed dose without consulting your doctor.
Consult your doctor before discontinuing the medication; do not stop taking it without their guidance.
Adhere to the dietary recommendations given by your doctor.

Valparin Chrono 300 Tablet is taken orally.

Side Effects of Valparin Chrono 300 Tablet 15

Valparin Chrono 300 Tablet may have the following common side effects:

Nausea
Vomiting
Diarrhoea
Abdominal pain
Drowsiness
Dizziness
Tremor: This refers to involuntary, rhythmic muscle contraction leading to shaking movements in one or more parts of your body.
Weight gain
Hair loss
Menstrual irregularities: You might notice a change in your menstrual cycle, such as missed periods or heavy bleeding.

Managing the Side Effects:

Most side effects are temporary and generally harmless, which resolve upon discontinuing the use of Valparin Chrono 300 Tablet. However, if you experience any serious side effects or worsening of any of the symptoms, please consult your doctor.

Here are some tips to manage common side effects:

Nausea or Abdominal pain: If you experience nausea or abdominal pain, consult your doctor for advice on managing these side effects. Follow the dietary recommendations provided by your doctor.
Drowsiness: Avoid activities your doctor has advised against and follow their recommendations.

How Valparin Chrono 300 Tablet 15 Works?

Valparin Chrono 300 Tablet contains sodium valproate/valproic acid (300 mg), which acts on your body as follows:

Increases GABA Levels: Sodium valproate increases the levels of gamma-aminobutyric acid (GABA), a substance that reduces brain activity. This helps stabilise electrical activity in the brain, minimising the occurrence of seizures and controlling mood swings associated with bipolar disorder.
Inhibits GABA Transaminase: Sodium valproate also inhibits an enzyme called GABA transaminase, which breaks down GABA. Doing so prevents the breakdown of GABA, ensuring stable levels of this inhibitory neurotransmitter in your brain.

Pregnancy

Valparin Chrono 300 Tablet is contraindicated during pregnancy, especially if you have epilepsy or bipolar disorder. If you are pregnant or planning to conceive, discuss this with your doctor before starting this medicine.

Breastfeeding

If you are breastfeeding, caution is needed while using Valparin Chrono 300 Tablet. It's best to consult your doctor before taking this medicine.

Alcohol

You should avoid consuming alcohol while taking Valparin Chrono 300 Tablet as it may increase the risk of side effects such as drowsiness and dizziness.

Liver

Valparin Chrono 300 Tablet should not be taken if you have liver disease or significant hepatic dysfunction. If you have liver problems, discuss them with your doctor before starting this medication.

Kidney

Caution is advised when using Valparin Chrono 300 Tablet if you have a history of kidney problems. Always consult your doctor before starting this medication.

Using Machines & Driving

This medication can cause side effects like drowsiness and dizziness which may affect your ability to drive or operate machinery. Exercise caution until you know how the medicine affects you.

Allergy

Do not take Valparin Chrono 300 Tablet if you are allergic to sodium valproate or any other ingredients. Inform your doctor beforehand about any known allergies.

Children

Caution is advised when giving Valparin Chrono 300 Tablet to children under 2 years of age due to a higher risk of serious liver damage. Always consult your doctor before giving any medicine to a child.

Older Patients

Older patients should take Valparin Chrono 300 Tablet under medical supervision as they may be more susceptible to its side effects. Caution is advised if patients are above 70 years of age. Your doctor will guide you based on your health status.

Interactions of Valparin Chrono 300 Tablet 15

Drug-Drug Interactions

Valparin Chrono 300 Tablet interacts with the following medicines:

Anticonvulsants: Medicines like carbamazepine and lamotrigine may interact with Valparin Chrono 300 Tablet, potentially altering their effectiveness or increasing the risk of side effects.
Antipsychotics: Medications such as quetiapine and olanzapine can interact with Valparin Chrono 300 Tablet, possibly leading to changes in medicine action or an increased risk of side effects.
Benzodiazepines: When taken with Valparin Chrono 300 Tablet, benzodiazepines like diazepam and lorazepam can have their effects altered.
Anticoagulants: Warfarin can interact with Valparin Chrono 300 Tablet, potentially affecting the blood-thinning effects of the anticoagulant.
Antidepressants: Antidepressants such as amitriptyline and nortriptyline may interact with Valparin Chrono 300 Tablet, potentially leading to altered medicinal effects or increased risk of side effects.
Cholesterol-lowering agents: Cholestyramine might affect how Valparin Chrono 300 Tablet works in your body.

Drug-Food Interactions

Valparin Chrono 300 Tablet does not interact with specific food items.

Drug-Disease Interactions

Valparin Chrono 300 Tablet interacts with the following diseases:

Liver Disease: Individuals with liver disease should be cautious as Valparin Chrono 300 Tablet could worsen their condition.
Urea Cycle Disorders: Patients suffering from urea cycle disorders should avoid taking this medication as it can exacerbate the condition.

Daily Dose

The daily intake of Valparin Chrono 300 Tablet should be as guided by your doctor. This could alter based on personal factors such as how severe your condition is and how you respond to the medication. It's crucial to stick to the prescribed dosage and not surpass it without your doctor's advice.

Over Dose

If you accidentally take more Valparin Chrono 300 Tablet than recommended, you might feel drowsy, dizzy or have an upset stomach. If these symptoms persist, it's wise to inform your doctor.

Missed Dose

In case you forget to take your regular dose of Valparin Chrono 300 Tablet, take it as soon as you remember. However, if it's nearing the time for the next dose, skip the one you missed and continue with your usual schedule. Don't increase your dose without discussing it with your doctor first.

Keep your Valparin Chrono 300 Tablet dry, away from light and moisture.
The ideal storage temperature is below 30°C.
Ensure the medicine is always out of reach of children.
Remember to check the expiry date before use. Never use it past this date.

If you're taking Valparin Chrono 300 Tablet for epilepsy, try to maintain a regular sleep pattern. Irregular sleep can sometimes trigger seizures.
If you are using this medication for bipolar disorder, consider incorporating daily exercise into your routine. Physical activity can help manage mood swings effectively. Always consult your doctor before starting any new exercise regimen.

Fact Box

Drug Category	GABA Level Increaser
Therapeutic Category	Anticonvulsant
Available Dosage Types	Tablet
Habit Forming	No
Ailment	Epilepsy, Bipolar Disorder, Migraine

What is Valparin Chrono 300 Tablet used for?

This medicine is primarily used to manage various types of seizures and manic episodes in bipolar disorder and to prevent migraine headaches.

How does Valparin Chrono 300 Tablet work?

It works by increasing levels of a brain chemical called gamma-aminobutyric acid (GABA), which helps control mood swings and reduce seizure activity.

Can I take this medicine if I am pregnant?

No, you should avoid taking Valparin Chrono 300 Tablet during pregnancy as it can cause congenital malformations and neurodevelopmental disorders in the unborn baby.

What are the common side effects of this medicine?

Common side effects include nausea, diarrhoea, abdominal pain, drowsiness, dizziness, weight gain, hair loss, and menstrual irregularities.

Can I take other medications along with Valparin Chrono 300 Tablet?

Certain medicines may interact with Valparin Chrono 300 Tablet. Always consult your doctor before starting any new medicine while taking this one.

What precautions should I take while using this medicine?

Regular monitoring of liver function and blood counts is needed. Women of childbearing age should use effective contraception to avoid pregnancy while taking this medication.

How should I store Valparin Chrono 300 Tablet?

Store the tablets at room temperature (15-30°C), away from light and moisture. Make sure they are kept out of reach of children.

Certified Content

Written by

Dr. Sachin Singh

Medical Team Lead | 5 years

MBBS

Reviewed by

Dr. Meenakshi Maruwada

Medical Content Writer & Strategist | 8 years

BDS, PGCAD, GMHE (IIM-B)

Check out Editorial Policy

Manufacturer details

CTS No.117-B L & T Business Park, Saki Vihar Rd, Powai, Mumbai, Maharashtra 400072

Country of origin: INDIA

References

NHS UK. (n.d.). Sodium valproate. NHS. Retrieved April 1, 2024, from https://www.nhs.uk/medicines/sodium-valproate/
U.S. Food and Drug Administration. (n.d.). [Valproic Acid]. FDA. Retrieved April 1, 2024, from https://www.fda.gov/media/175681/download?attachment
Valproic acid: MedlinePlus drug information. (n.d.-b). https://medlineplus.gov/druginfo/meds/a682412.html
Rahman, M., Awosika, A. O., & Nguyen, H. (2024b, March 19). Valproic acid. StatPearls - NCBI Bookshelf. https://www.ncbi.nlm.nih.gov/books/NBK559112/

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