Viropil Tablet 30

Emcure Pharmaceuticals Ltd

BOTTLE of 90 Units
BOTTLE of 30 Units

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Old MRP ₹3863.53

MRP ~~₹3622.06~~

₹2897.65

₹120.74/Units

20% off

*MRP inclusive of all taxes

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Prescription required for this medicine

Store Below 30^o C

Composition

Dolutegravir (50 Mg) + Lamivudine (300 Mg) + Tenofovir Disoproxil Fumarate (300 Mg)

Viropil Tablet is used to manage HIV-1 infection in both adults and children. This combination antiretroviral medication is also effective in initiating treatment for individuals who have not received HIV-1 treatment or as a replacement for those with suppressed viral loads and no history of treatment failure.

Before starting this medicine, consult your doctor to determine the right dosage and frequency. Inform your doctor about any pre-existing conditions or ongoing medications. If you notice any side effects, notify your doctor immediately and continue taking the medicine as prescribed for optimal results.

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Viropil Tablet is used to treat human immunodeficiency virus (HIV) infection in adults and children weighing at least 40 kg. It can be prescribed for those starting antiretroviral therapy for the first time or to replace an existing regimen in patients responding well with no history of treatment failure.

Swallow the tablet whole with a glass of water. Do not crush or chew it.
You can take this medicine with or without food.
Do not take more than the recommended dose without consulting your doctor.
If you decide to stop taking this medicine, ensure you first consult your doctor.

Viropil Tablet is taken orally.

Viropil Tablet may have the following common side effects:

Insomnia
Headache
Fatigue

Managing the Side Effects:

Most side effects are temporary and generally harmless, which resolve on discontinuing the use of Viropil Tablet. However, if you experience any serious side effects or worsening of any of the symptoms, please consult your doctor.

Here are some general guidelines for managing common side effects:

Insomnia: If you find it difficult to sleep after taking Viropil Tablet, consider taking it in the morning instead of at night.
Fatigue: If you feel worn out after taking this medicine, it may help to take it just before bed.

Viropil Tablet contains three active ingredients that work together to inhibit key steps in the HIV replication cycle:

Dolutegravir (50 mg): This component binds to the active site of the HIV integrase and blocks the strand transfer step of retroviral DNA integration, a vital step in the HIV replication cycle.
Lamivudine (300 mg): Lamivudine is a synthetic nucleoside analogue that inhibits HIV reverse transcriptase after its intracellular transformation into its active 5'-triphosphate metabolite. This results in the termination of the DNA chain.
Tenofovir Disoproxil Fumarate (300 mg): This component is an acyclic nucleoside phosphonate diester analogue of adenosine monophosphate. After undergoing diester hydrolysis and phosphorylation, it inhibits the activity of HIV-1 reverse transcriptase by competing with the natural substrate deoxyadenosine 5'-triphosphate and causing DNA chain termination after incorporation into DNA.

Pregnancy

Caution is advised while taking Viropil Tablet if you are pregnant. It is best to consult your doctor before taking this medicine.

Breastfeeding

Viropil Tablet is contraindicated for breastfeeding or lactating women. Consult your doctor to understand the potential risks and benefits.

Alcohol

To ensure the effectiveness of the medicine, it's recommended to limit alcohol consumption.

Liver

All patients should be tested for hepatitis B virus (HBV) before starting with Viropil Tablet as severe acute exacerbations of hepatitis B have been reported. If you have liver problems, discuss them with your doctor before starting Viropil Tablet.

Kidney

Caution is required for using Viropil Tablet if you have a history of any kidney problems. The medicine is not recommended in patients with severe renal impairment or end-stage renal disease requiring dialysis.

Using Machines & Driving

No specific information is available regarding the effect of Viropil Tablet on driving or operating machinery. However, if you feel dizzy or sleepy after taking this medicine, avoid these activities until you feel better.

Allergy

If you are allergic to any ingredients in Viropil Tablet, discontinue its use immediately and consult your doctor.

Children

Viropil Tablet can be given to children weighing at least 40 kg under medical supervision. Always consult your doctor before giving any medicine to a child.

Older Patients

Older patients should take Viropil Tablet under medical supervision as they may be more susceptible to its side effects. Your doctor will guide you based on your health status.

Drug-Drug Interactions

Viropil Tablet interacts with the following medicines:

Anti-epileptic medicines: Medications like carbamazepine, oxcarbazepine, phenobarbital, and phenytoin can reduce the blood levels of dolutegravir, one of the active ingredients in Viropil Tablet, potentially reducing its effectiveness.
Tuberculosis (TB) medication: Rifampin, a TB medication, can also decrease dolutegravir levels in your body.
Herbal supplements: St. John's wort, a herbal supplement often used for depression, can reduce the effect of dolutegravir due to its strong inducing properties.
Antiviral medicines: Some antiviral medications like adefovir dipivoxil and cidofovir can increase the concentration of lamivudine or tenofovir, two other ingredients in Viropil Tablet, potentially increasing the risk of side effects.

Drug-Food Interactions

Viropil Tablet has no known significant interactions with any food items.

Drug-Disease Interactions

Viropil Tablet interacts with the following diseases:

Hepatitis B: If you have hepatitis B virus (HBV), stopping treatment with lamivudine or tenofovir, two components of Viropil Tablet, could lead to a serious flare-up of your hepatitis B.
Kidney disease: If you have severe kidney problems or end-stage renal disease requiring dialysis, Viropil Tablet is not recommended as it may worsen your condition.
Lactic Acidosis/Severe Hepatomegaly with Steatosis: If you have these conditions or develop symptoms suggesting them while on Viropil Tablet, treatment should be suspended as it could aggravate these conditions.

Daily Dose

If you mistakenly take more than the prescribed dose of Viropil Tablet, you might experience symptoms like headache, insomnia, or fatigue. However, if these symptoms persist or become severe, it's important to inform your doctor.

Over Dose

If you forget to take a dose of Viropil Tablet, don't worry. Take it as soon as you remember. But if it's almost time for your next dose, skip the one you missed and continue with your regular schedule. Remember not to increase your dosage without speaking to your doctor.

Missed Dose

Store Viropil Tablet below 30°C, ideally in a cool, dry place.
Avoid exposure to excessive light and moisture.
Keep the tablet bottle tightly closed when not in use.
Always keep Viropil Tablet out of reach of children.
Make sure to use this medicine before its expiry date.

If you're on Viropil Tablet, maintaining a healthy diet can support your overall well-being. Include a variety of fruits and vegetables in your meals as they are rich in antioxidants and can strengthen your immune system.
Regular moderate exercise, like walking or yoga, can help improve your overall health and enhance your body's ability to cope with illness. Remember to consult your doctor before starting any new exercise regimen.

Fact Box

Available Dosage Types	Tablet
Habit Forming	No
Ailment	HIV-1 Infection
Drug Category	Integrase Inhibitor, NRTI, NtRTI
Therapeutic Category	Antiretroviral

What is Viropil Tablet used for?

Viropil Tablet is used to manage HIV-1 infection in adults and children above 40kg, alongside other antiretroviral agents.

How does Viropil Tablet work?

The medicine contains three active ingredients that inhibit crucial steps in the HIV replication cycle, thereby helping to manage the infection.

Can I take Viropil Tablet with or without food?

Consume plenty of water and healthy fluids to avoid dehydration.

Can Viropil Tablet cure my HIV-1 infection completely?

No, Viropil Tablet manages HIV-1 infection but does not cure it. Regular use under a doctor's guidance is key for effective management.

Is it safe to use Viropil Tablet during pregnancy or while breastfeeding?

HIV-1 infected mothers are advised not to breastfeed. Always consult your doctor for advice.

What should I do if I miss a dose of Viropil Tablet?

If you miss a dose, take it as soon as you remember unless it's time for the next dose. Never double dose; consult your doctor.

Can I stop taking Viropil Tablet if I feel better?

No, discontinuing Viropil Tablet without a doctor's consent may lead to development of resistance in the body against the medicine.

Last Updated On 14 Nov. 2025 | 8:14AM (IST)

Certified Content

Written by

Dr Nikita Lobo

Medical Content Reviewer | 8 years

BDS, MDS

Reviewed by

Dr. Chhavi Rosha

Medical Content Writer | 9 years

BAMS, FMC, MD Resident

Check out Editorial Policy

Manufacturer details

Emcure House, T 184, M.I.D.C. Bhosari, Pune 411026

Country of origin: INDIA

Expiry on or after: March 2026

In case of any issues, contact us:

support@truemeds.in|09240250346

Address: 6th floor, Urmi Corporate Park Solaris, Saki Vihar Road, Andheri East, Mumbai 400071

References

Dolutegravir (Tivicay) Package Insert | DAIDS Regulatory Support Center (RSC). (n.d.). https://rsc.niaid.nih.gov/clinical-research-sites/dolutegravir-tivicay-package-insert
Dolutegravir: Uses, interactions, mechanism of action | DrugBank Online. (n.d.). DrugBank. https://go.drugbank.com/drugs/DB08930
MedlinePlus. (2021). Lamivudine. Retrieved 1 July 2024, from https://medlineplus.gov/druginfo/meds/a696011.html
MedlinePlus. (2021). Tenofovir Disoproxil Fumarate. Retrieved 1 July 2024, from https://medlineplus.gov/druginfo/meds/a602018.html

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Disclaimer

We, at Truemeds make a diligent attempt to deliver accurate, expert- drafted and thoroughly reviewed medicine related information to our consumers. However, it should, by no means, be considered a substitute for prescription from a certified doctor or a trustworthy doctor-patient relationship. In fact we detest any form of self medication without expert advice. The sole purpose of the information on our portal is to educate our consumers, which helps improve the communication between a doctor and a patient. The information by no means is complete in its entirety and should not be used to diagnose or treat any medical condition. No amount of information can replace the experience and expertise of a doctor, therefore his/her advice always holds priority and should be followed appropriately.

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