Zyrik 300 Mg Tablet 10

Zyrik 300 Tablet 10

Cipla Ltd.

Strip of 10 Units

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MRP ~~₹63.05~~

₹33.63

₹6.31/Units

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Composition

Allopurinol (300 Mg)

Strength:

300 MG 100 MG

Zyrik 300 Tablet 10 is primarily used for the management of gout, a condition characterised by an excessive amount of uric acid in the body. It belongs to a class of medications known as xanthine oxidase inhibitors.

Besides its main use, this medicine is also used to prevent certain types of kidney stones. In patients undergoing cancer chemotherapy, it is utilised to prevent an increase in uric acid levels.

You should take this medicine exactly as your doctor instructs. Before starting this medicine, it's important to let your doctor know about any existing health conditions or any other medications that you're currently taking. If you experience any side effects while taking this medicine, notify your doctor right away. For optimal results, continue taking the medicine for the duration prescribed by your doctor.

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Zyrik 300 Tablet 10 is used for the following:

This medicine helps to prevent and manage attacks of gout, a painful condition caused by excess uric acid in your body.
Continued use can help prevent complications of gout such as kidney stones and joint damage.
It can help in managing kidney stones formed due to excess uric acid.
For patients undergoing cancer treatment, this medicine helps to avoid the spike in uric acid levels that can occur during chemotherapy.

Directions for Use of Zyrik 300 Tablet 10

Swallow the tablet whole with a glass of water.
Avoid crushing or chewing the tablet.
Do not take more than the recommended dose without consulting your doctor.
Don't stop taking this medicine without first discussing it with your doctor.

Zyrik 300 Tablet 10 is taken orally.

Zyrik 300 Tablet 10 may have the following common side effects:

Nausea
Diarrhoea
Stomach upset
Drowsiness
Skin rash
Numbness or tingling in arms or legs: You may feel a sensation of pins and needles or a lack of sensitivity in these areas.

Managing the Side Effects:

Most side effects are temporary and generally harmless, which resolve on discontinuing the use of Zyrik 300 Tablet 10. However, if you experience any serious side effects or worsening of any of the symptoms, please consult your doctor.

Here are two tips to manage common side effects:

Stomach upset: Try taking Zyrik 300 Tablet 10 after a light meal to lessen this effect.
Drowsiness: Consider taking this medication at night, which may help avoid daytime drowsiness.

Zyrik 300 Tablet 10 contains Allopurinol (300 mg), which works on the body as follows:

Inhibition of Xanthine Oxidase: Allopurinol blocks an enzyme in your body called xanthine oxidase. This enzyme plays a crucial role in the biochemical process leading up to the formation of uric acid.
Reduction of Uric Acid: By inhibiting the action of xanthine oxidase, allopurinol effectively reduces the levels of uric acid in the blood. This reduction helps to manage gout and prevents the formation of certain types of kidney stones.

Pregnancy

Zyrik 300 Tablet 10 is contraindicated during pregnancy. If you are pregnant or planning to conceive, it's crucial to discuss this with your doctor before starting this medicine.

Breastfeeding

Zyrik 300 Tablet 10 is contraindicated for breastfeeding women. It's advisable to consult your doctor to understand the potential risks and benefits.

Alcohol

Caution is advised when consuming alcohol while taking Zyrik 300 Tablet 10, as it may exacerbate certain side effects and worsen your condition.

Liver

If you have a history of kidney problems, it is a good idea to consult your doctor before taking Zyrik 300 Tablet 10.

Kidney

If you have a history of kidney problems, it is a good idea to consult your doctor before taking Zyrik 300 Tablet 10.

Using Machines & Driving

Dizziness, drowsiness, and visual disturbances may occur with Zyrik 300 Tablet 10. Caution should be exercised when driving or operating machinery.

Allergy

Zyrik 300 Tablet 10 is contraindicated in patients with a history of hypersensitivity to allopurinol or chemically related medicines like mercaptopurine or azathioprine.

Children

Caution is advised while giving Zyrik 300 Tablet 10 to children under 18 years of age. Always consult your doctor before giving any medicine to a child.

Older Patients

Older patients should take Zyrik 300 Tablet 10 under medical supervision as they may be more susceptible to its side effects. Caution is advised if patients are above 70 years of age. Your doctor will guide you based on your health status.

Drug-Drug Interactions

Zyrik 300 Tablet 10 interacts with the following medicines:

Blood thinners: Medicines like warfarin or aspirin may interact with Zyrik 300 Tablet 10, potentially increasing your risk of bleeding.
Chemotherapy medicines: Medicines such as mercaptopurine, azathioprine, or capecitabine may have their effectiveness reduced when taken with Zyrik 300 Tablet 10.
Anti-retroviral medicines: If you're taking didanosine, an anti-HIV medicine, it could interact with Zyrik 300 Tablet 10, potentially leading to increased side effects.
Diuretics: Thiazide diuretics like hydrochlorothiazide may interact with Zyrik 300 Tablet 10, which could lead to increased uric acid levels.

Drug-Food Interactions

There are no known specific food interactions associated with Zyrik 300 Tablet 10.

Drug-Disease Interactions

Zyrik 300 Tablet 10 interacts with the following diseases:

Liver disease: If you have a history of liver disease, Zyrik 300 Tablet 10 might exacerbate your condition.
Kidney disease: Those suffering from kidney disease should exercise caution while on this medication, as it can affect kidney function.
Diabetes: Zyrik 300 Tablet 10 might impact blood sugar control, making it important to monitor your glucose levels closely when on this medication.

Daily Dose

The daily dose of Zyrik 300 Tablet 10 should be taken as recommended by your doctor. Your dosage may vary based on factors such as the severity of your condition and how you respond to the medicine. It's crucial to adhere to the prescribed dosage and never exceed it without consulting your doctor.

Over Dose

If you accidentally take more than your prescribed dose of Zyrik 300 Tablet 10, you might experience side effects like hot flashes, headache, or nausea. If these symptoms persist or worsen, it's important to inform your doctor.

Missed Dose

If you forget to take your Zyrik 300 Tablet 10, consume it as soon as you remember. However, if it's nearly time for your next dose, skip the missed one and resume your usual dosage schedule. Always consult your doctor before making any changes to your dosage.

Keep Zyrik 300 Tablet 10 in a tightly closed container.
Store it at room temperature.
Protect the medicine from light and moisture.
Always keep Zyrik 300 Tablet 10 out of reach of children.
Use the product before its expiry date.

Drinking plenty of fluids: Consuming at least 8 glasses (8 ounces each) of water daily is beneficial when you're taking Zyrik 300 Tablet 10. It helps in flushing out excess uric acid from your body.
Limiting alcohol intake: Alcohol may decrease the effectiveness of Zyrik 300 Tablet 10. Therefore, it's wise to cut down on or completely avoid alcoholic beverages while managing your condition with this medicine.

Fact Box

Drug Category	Xanthine Oxidase Inhibitor
Therapeutic Category	Antigout Agent
Available Dosage Types	Tablet
Habit Forming	No
Ailment	Gout, Certain Types of Kidney Stones

What is Zyrik 300 Tablet 10 used for?

Zyrik 300 Tablet 10 helps manage gout and certain types of kidney stones by reducing uric acid in the body.

How does Zyrik 300 Tablet 10 work?

The medicine works as a nonsteroidal aromatase inhibitor, reducing the production of estrogen, a hormone that stimulates breast cancer cell growth.

How should I take Zyrik 300 Tablet 10?

You should take this medicine as directed by your doctor.

What if I miss a dose of Zyrik 300 Tablet 10?

If you miss a dose, take it when you remember. If it's close to your next dose time, skip the missed dose.

When will Zyrik 300 Tablet 10 start working?

Allopurinol starts reducing blood uric acid levels within 2-3 days, but full effects may take several weeks to show.

Are there any side effects of Zyrik 300 Tablet 10?

Common side effects include stomach upset, drowsiness, and skin rash. Uncommon but serious side effects should be reported to your doctor.

Is there anything I should avoid while taking Zyrik 300 Tablet 10?

It's recommended to limit alcohol and be cautious when doing tasks requiring alertness as this medicine may cause drowsiness.

Certified Content

Written by

Dr Nikita Lobo

Medical Editor & Reviewer | 7 years

BDS, MDS

Reviewed by

Dr. Chhavi Rosha

Health & Medical Content Writer | 8 years

BMS, FMC, MD Resident

Check out Editorial Policy

Manufacturer details

Cipla House, Peninsula Business Park, Ganpatrao Kadam Marg, Lower Parel, Mumbai-400013

Country of origin: INDIA

References

PRODUCT INFORMATION ZYLOPRIM ® (allopurinol) 100-mg Scored Tablets and 300-mg Scored Tablets Rx Only. (n.d.). https://www.accessdata.fda.gov/drugsatfda_docs/label/2018/016084s044lbl.pdf
HIGHLIGHTS OF PRESCRIBING INFORMATION. (2024). [Prescribing information]. In FULL PRESCRIBING INFORMATION. https://www.accessdata.fda.gov/drugsatfda_docs/label/2024/018832s056s058s061,018877s063s065s068lbl.pdf
APOTEX INC. (2017). PRODUCT MONOGRAPH: ALLOPURINOL allopurinol tablets, USP 300 mg. https://pdf.hres.ca/dpd_pm/00037852.PDF
Becker, M. A., Fitz-Patrick, D., Choi, H. K., Dalbeth, N., Storgard, C., Cravets, M., & Baumgartner, S. (2015). An open-label, 6-month study of allopurinol safety in gout: The LASSO study. Seminars in Arthritis and Rheumatism, 45(2), 174–183. https://doi.org/10.1016/j.semarthrit.2015.05.005
Allopurinol: Uses, interactions, mechanism of action | DrugBank Online. (n.d.). DrugBank. https://go.drugbank.com/drugs/DB00437

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