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Benzalkonium Chloride + Brinzolamide

Uses of Benzalkonium Chloride + Brinzolamide

  • The primary use of Benzalkonium Chloride + Brinzolamide is to manage elevated intraocular pressure in patients with open-angle glaucoma or ocular hypertension. This medicine belongs to the group of carbonic anhydrase inhibitors and antimicrobial preservatives.

  • It is also used when a single medication fails to sufficiently control eye pressure, thereby helping to prevent nerve damage and vision loss.

Side effects of Benzalkonium Chloride + Brinzolamide

  • Temporary blurred vision

  • Taste disturbance

  • Eye discomfort

  • Eye redness

  • Headache

How Benzalkonium Chloride + Brinzolamide works

  • Benzalkonium Chloride + Brinzolamide belongs to the category of ophthalmic medications for reducing intraocular pressure.

  • Brinzolamide is a carbonic anhydrase inhibitor. It reduces the fluid produced within the eye, known as aqueous humour. This decrease in fluid production and buildup leads to a reduction in intraocular pressure.

  • Benzalkonium Chloride is a quaternary ammonium compound. It is a preservative in the eye drop formulation, preventing bacterial contamination and ensuring safe multi-dose usage.

Certified content

Written By

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Dr. Michelle FrankMedical Content Writer| 8 years

Doctor of Medicine

Reviewed By

Dr. Chhavi Rosha
Dr. Chhavi Rosha Health & Medical Content Writer| 8 years

BMS, FMC, MD Resident

Expert Advice

Dosage Forms Available

  • Benzalkonium Chloride + Brinzolamide is applied topically (eye drops).

Age and Dose Restrictions

  • This medicine is meant for adults and children above 2 years of age.

Contraindications

  • This medicine is contraindicated in patients with known hypersensitivity to brinzolamide or benzalkonium chloride.

  • It is also contraindicated in patients with known hypersensitivity to sulphonamides and those on high-dose salicylate therapy due to the risk of metabolic acidosis.

Other Medications to Avoid

  • This combination may interact with several medications, including other eye drops containing preservatives (such as thimerosal), intraocular pressure-lowering agents (like timolol or bimatoprost), and anti-inflammatory eye drops (such as dexamethasone). These interactions can affect the efficacy and safety of the eye treatments.

Overdose and Missed Dose

  • In case you happen to put a few extra drops of this medicine in your eye, do not panic. Rinse your eyes with clean water at room temperature. If any symptoms persist or worsen, inform your doctor.

  • If you miss a dose, put it on as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double the dose.

Management of Side Effects

Most side effects are temporary and generally harmless and resolve when discontinuing this medicine. However, if you experience any severe side effects or worsening of any of the symptoms, please consult your doctor.

  • For eye discomfort or foreign body sensations in the eyes, rinse your eyes with clean, room-temperature water.

  • For headaches, resting or lying in a dark room may help.

Use in Driving and Operating Machinery

  • Benzalkonium Chloride + Brinzolamide may cause temporary blurred vision after administration. If this occurs, it is advised not to drive or operate machinery until your vision is clear.

Use in Pregnancy and Lactation

  • Consult your doctor before using this medicine if you are pregnant, planning a pregnancy, or breastfeeding.

Caution in Other Conditions

  • This medication should be used with caution in patients with renal impairment as Brinzolamide and its metabolites are predominantly excreted by the kidneys.

Special Dietary and Lifestyle Recommendations

  • Make sure to get regular eye examinations to monitor the progress of your treatment.

  • Maintain a healthy diet rich in fruits and vegetables which are good for eye health such as carrots, spinach and oranges.

Frequently asked questions

Benzalkonium chloride + Brinzolamide is not associated with impacting hormonal balance. This combination medicine is primarily used for eye conditions like glaucoma. If you have concerns, consult your healthcare provider.

No, Benzalkonium Chloride + Brinzolamide does not contain any steroids. It contains a carbonic anhydrase inhibitor and a preservative, which work together to manage high eye pressure in conditions like glaucoma.

Benzalkonium chloride + Brinzolamide is not typically associated with affecting sleep. This combination medicine is used to manage eye conditions, such as glaucoma. If you experience sleep disturbances, consult your healthcare provider.

The onset of action may vary for each individual, but typically you may start seeing effects within two weeks. However, it may take up to four weeks to see full effects on eye pressure.

Benzalkonium Chloride + Brinzolamide is a prescription medicine and is not available over the counter.

The duration of treatment with Benzalkonium Chloride + Brinzolamide is determined by your doctor based on your condition and response to the therapy. It is important to continue using the medicine as prescribed even if your symptoms improve.

Benzalkonium chloride + Brinzolamide is not generally associated with affecting fertility. This combination medicine is primarily used for eye conditions like glaucoma. If you have specific concerns, consult your healthcare provider.

Terms & Conditions


Benzalkonium Chloride + Brinzolamide in other salts

BENZALKONIUM CHLORIDE + CHOLINE SALICYLATE + LIDOCAINE / LIGNOCAINEBENZALKONIUM CHLORIDE + ZINC OXIDEBENZALKONIUM CHLORIDE + BROMFENAC + MOXIFLOXACINBENZALKONIUM CHLORIDE + OFLOXACINBRINZOLAMIDEBENZALKONIUM CHLORIDE + CYCLOPENTOLATEBENZALKONIUM CHLORIDE + CIPROFLOXACINBENZALKONIUM CHLORIDE + CIPROFLOXACIN + DEXAMETHASONEBENZALKONIUM CHLORIDE + FLUOROMETHOLONEBENZALKONIUM CHLORIDE + FLUOROMETHOLONE + TOBRAMYCINBENZALKONIUM CHLORIDE + GATIFLOXACINBENZALKONIUM CHLORIDE + DEXAMETHASONE + OFLOXACINBENZALKONIUM CHLORIDE + NEPAFENACBENZALKONIUM CHLORIDE + MOXIFLOXACIN + PREDNISOLONEBENZALKONIUM CHLORIDE + TOBRAMYCINBENZALKONIUM CHLORIDE + CHOLINE SALICYLATEBENZALKONIUM CHLORIDE + DEXAMETHASONE + TOBRAMYCINBENZALKONIUM CHLORIDE + BRIMONIDINE + TIMOLOLALCAFTADINE + BENZALKONIUM CHLORIDEBENZALKONIUM CHLORIDE + TIMOLOLBENZALKONIUM CHLORIDE + FLUCONAZOLEBENZALKONIUM CHLORIDE + KETOROLAC + MOXIFLOXACINBENZALKONIUM CHLORIDE + LATANOPROSTBENZALKONIUM CHLORIDE + OLOPATADINE HYDROCHLORIDEBENZALKONIUM CHLORIDE + BRIMONIDINEBENZALKONIUM CHLORIDE + PHENYLEPHRINE + TROPICAMIDEBENZALKONIUM CHLORIDE + BEPOTASTINEBENZALKONIUM CHLORIDE + BRIMONIDINE + BRINZOLAMIDEBENZALKONIUM CHLORIDE + BIMATOPROSTBENZALKONIUM CHLORIDE + BIMATOPROST + TIMOLOLBENZALKONIUM CHLORIDE + BRINZOLAMIDE + TIMOLOLBRIMONIDINE + BRINZOLAMIDEBENZALKONIUM CHLORIDE + CYCLOSPORINBENZALKONIUM CHLORIDE + KETOROLAC + OLOPATADINEBENZALKONIUM CHLORIDE + DORZOLAMIDEBENZALKONIUM CHLORIDE + DORZOLAMIDE + TIMOLOLBENZALKONIUM CHLORIDE + GATIFLOXACIN + PREDNISOLONEBENZALKONIUM CHLORIDE + LATANOPROST + TIMOLOLBENZALKONIUM CHLORIDE + LOTEPREDNOLBENZALKONIUM CHLORIDE + LOTEPREDNOL + TOBRAMYCINBENZALKONIUM CHLORIDE + DEXAMETHASONE + MOXIFLOXACINBENZALKONIUM CHLORIDE + LOTEPREDNOL + MOXIFLOXACINBENZALKONIUM CHLORIDE + BROMFENACBENZALKONIUM CHLORIDE + MOXIFLOXACINBENZALKONIUM CHLORIDE + OLOPATADINEBENZALKONIUM CHLORIDE + PREDNISOLONEBENZALKONIUM CHLORIDE + TIMOLOL + TRAVOPROSTBENZALKONIUM CHLORIDE + TRAVOPROSTBENZALKONIUM CHLORIDE + NATAMYCINBENZALKONIUM CHLORIDE + CAMPHOR + MENTHOL + NAPHAZOLINE HYDROCHLORIDE + PHENYLEPHRINE HYDROCHLORIDEBENZALKONIUM CHLORIDE + NETARSUDILBENZALKONIUM CHLORIDE + GANCYCLOVIR
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