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Cefixime

Antibiotic

Uses of Cefixime

  • Cefixime is an antibiotic used to treat bacterial infections.
  • It is prescribed for bacterial infections affecting various body regions, including the ears, nose, and sinuses (e.g., sinusitis), throat (e.g., tonsillitis, pharyngitis), respiratory system (e.g., bronchitis, pneumonia), and the urinary tract (e.g., cystitis and kidney infections).

Side effects of Cefixime

  • Diarrhoea 
  • Blood in stool

How Cefixime works

  • Cefixime, an antibiotic classified as a third-generation cephalosporin akin to ceftriaxone and cefotaxime, exhibits robust stability in the presence of beta-lactamase enzymes. This stability renders many organisms resistant to penicillins and certain cephalosporins due to beta-lactamases susceptible to cefixime. The antibacterial efficacy of cefixime stems from its ability to inhibit mucopeptide synthesis in the bacterial cell wall. Like all beta-lactam antibiotics, cefixime binds to designated penicillin-binding proteins (PBPs) within the bacterial cell wall. This binding leads to the hindrance of the third and final phase of bacterial cell wall synthesis. Subsequently, cell lysis occurs through the mediation of bacterial cell wall autolytic enzymes, including autolysins. It is plausible that cefixime disrupts an autolysin inhibitor in this process.

Certified content

Written By

docImg
Amit SharmaClinical Health & Medical Writer| 3 Years

B. Pharm

Reviewed By

Amatul Ameen
Amatul Ameen Clinical Health & Medical Writer| 12 Years

B. Pharm, MSc.

Expert Advice

Dosage Forms Available

  • Cefixime is available for use via the oral route (tablet, chewable tablet, capsule, and suspension (liquid)).

Age and Dose Restrictions

  • This medicine is meant for adults and children above 10 years of age.

Contraindications

  • Cefixime is contraindicated in patients with known allergies to cefixime.

Other Medications To Avoid With This Medicine

  • Avoiding the use of anticoagulants (warfarin), anticonvulsants (carbamazepine), and vaccinations (including BCG, cholera vaccine, and typhoid vaccine) along with Cefixime. Prior consultation with your doctor is essential before considering any prescription or over-the-counter medications.

Overdose and Missed Dose

  • In case of an overdose of this medicine, inform your doctor and follow the advice accordingly.
  • If you forget to take this medicine, take it as soon as you remember. But avoid repeating the dose.

Use In Driving And Operating Machinery

  • Cefixime may affect your ability to drive or operate heavy machinery. Avoid driving if you feel dizzy after taking it.

Use in Pregnancy and Lactation

  • Cefixime is not recommended during pregnancy or breastfeeding.

Special Dietary & Lifestyle Recommendation

  • Avoid alcohol when you are taking Cefixime.
  • This medicine can be taken before or after meals.

Frequently asked questions

This medicine starts showing its effects within a few hours after consumption.

Avoid usage if you experience an allergic reaction (hypersensitivity) to Cefixime. It is advisable to seek advice from a doctor promptly.

Do not stop taking this medicine without consulting your doctor, even if you feel healthy.

Consult your doctor before taking this medicine if you have kidney or liver issues to ensure its safety and proper dosage.

No, this medicine does not affect contraception.

Terms & Conditions


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