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Methylergometrine

Uses of Methylergometrine

  • Methylergometrine is primarily used to manage postpartum haemorrhage, defined as excessive bleeding after childbirth, and belongs to ergot alkaloids.

  • Additionally, it is used to manage uterine atony (a condition where the uterus fails to contract adequately after childbirth, leading to excessive blood loss). In some cases, it may also be used to induce or augment labour contractions.

Side effects of Methylergometrine

  • Nausea

  • Vomiting

  • Abdominal pain or cramping

  • Headache

  • Dizziness

  • High blood pressure

How Methylergometrine works

  • Methylergometrine is an uterotonic agent (medication given after childbirth to help the uterus shrink back to its normal size to prevent excessive bleeding) and an ergot derivative.

  • It acts directly on the smooth muscles found within the uterus. This action stimulates and sustains uterine contractions. These contractions help to increase the tone, rate, and strength of rhythmic contractions within the uterus. This leads to a rapid and prolonged uterotonic effect. This uterotonic effect helps to squeeze the blood vessels in the wall of the uterus. This squeezing action reduces blood loss and helps stop bleeding.

  • Methylergometrine also boosts the effects of natural substances in your body called prostaglandins, which also help to contract the uterus.

Certified content

Written By

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Dr Nikita LoboMedical Editor & Reviewer| 7 years

BDS, MDS

Reviewed By

Dr. Chhavi Rosha
Dr. Chhavi Rosha Health & Medical Content Writer| 8 years

BMS, FMC, MD Resident

Expert Advice

Dosage Forms Available

  • Methylergometrine can be taken in intramuscular (injection), intravenous (injection) and orally (tablet) routes.

Age and Dose Restrictions

  • Methylergometrine is generally used in adult women, particularly during childbirth. It is not typically given to children or men.

Contraindications

  • This medicine is contraindicated in patients allergic to ergot alkaloids. It is also contraindicated in people with certain medical conditions such as high blood pressure, heart disease, peripheral vascular disease, or Raynaud's syndrome.

Other Medications to Avoid

  • Methylergometrine can interact with other ergot alkaloids (e.g., ergotamine, dihydroergotamine), azole antifungals (e.g., itraconazole, ketoconazole), macrolide antibiotics (e.g., erythromycin, clarithromycin), and "triptan" migraine medications (e.g., rizatriptan, sumatriptan).

Overdose and Missed Dose

  • An overdose of this medicine can cause symptoms such as nausea, vomiting, abdominal pain, headache, and dizziness. If this happens, you should consult your doctor immediately.
  • If you forget to take a dose of this medicine, take it as soon as you remember. But if your next dose is due soon, skip the missed dose and return to your regular medication schedule. Do not take a double dose to make up for a missed one.

Management of Side Effects

Most side effects are temporary and generally harmless and resolve when discontinuing this medicine. However, if you experience any severe side effects or worsening of any of the symptoms, please consult your doctor.

  • Avoid sudden changes in posture to avoid dizziness and lightheadedness.

Use in Driving and Operating Machinery

  • Methylergometrine can cause dizziness. This means it may affect your ability to drive or operate heavy machinery. If you feel dizzy after taking this medicine, do not drive or operate machinery until you feel well enough.

Use in Pregnancy and Lactation

  • This medicine should not be used during pregnancy as it can cause uterine contractions that could harm the unborn baby. It should also be avoided or used with caution during breastfeeding due to the potential for it to affect the nursing infant. Always consult your doctor before using this medicine if you are pregnant or breastfeeding.

Caution in Other Conditions

  • People with certain medical conditions, such as kidney or liver problems, should be cautious when using Methylergometrine.

Special Dietary and Lifestyle Recommendations

  • Do not eat or drink grapefruit products, as they may increase serum levels of Methylergometrine.

Frequently asked questions

Yes, Methylergometrine can be given after a cesarean section to help control postpartum hemorrhage (excessive bleeding after childbirth).

Methylergometrine is rapidly absorbed after administration and starts to work quickly. However, the exact time it takes to work can vary based on different factors. Consult your doctor for more information.

Methylergometrine should be used with caution in patients with a history of high blood pressure or cardiovascular disease. Always consult your doctor before starting any new medicine.

While there is no direct link between Methylergometrine and mood changes, being unwell can sometimes affect your mood. If you have concerns, consult your doctor.

Methylergometrine should be stored at room temperature, away from light and moisture. Always keep medicines out of reach of children.

No, you should not stop taking Methylergometrine unless advised by your doctor. Even if you feel better, it's important to finish the full course of treatment to ensure the condition is fully managed.

If you think you may be allergic to Methylergometrine, stop taking the medicine and consult your doctor immediately.

Terms & Conditions

Available medicines for METHYLERGOMETRINE
Methergin Injection 1ml
Methergin Injection 1ml
Dr. Reddys Laboratories Ltd
Pack of 1 ML
₹13.10
MRP ₹15.98
18.00% OFF
Methergin Tablet 10
Methergin Tablet 10
Dr. Reddys Laboratories Ltd
Pack of 10 Units
₹82.00
MRP ₹100.00
18.00% OFF
Methygene Tablet 10
Methygene Tablet 10
Intas Pharmaceuticals Ltd
Pack of 10 Units
₹49.94
MRP ₹100.09
50.10% OFF
Methyden 0.125 MG Tablet 10
Methyden 0.125 MG Tablet 10
Bmw Pharmaco India Pvt. Ltd.
Pack of 10 Units
₹31.98
MRP ₹39.00
18.00% OFF
Gotrin 0.125 MG Tablet 10
Gotrin 0.125 MG Tablet 10
Rekvina Pharmaceuticals
Pack of 10 Units
₹40.59
MRP ₹49.50
18.00% OFF
Utergin Tablet 10
Utergin Tablet 10
Maneesh Pharmaceuticals Ltd
Pack of 10 Units
₹72.92
MRP ₹88.93
18.00% OFF
Metergo 0.125 MG Tablet 10
Metergo 0.125 MG Tablet 10
Lupin Ltd
Pack of 10 Units
₹9.73
MRP ₹11.87
18.00% OFF
Methygin Tablet 10
Methygin Tablet 10
Intas Pharmaceuticals Ltd
Pack of 10 Units
₹82.02
MRP ₹100.02
18.00% OFF

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