Piperacillin + Tazobactam

Dosage Forms Available

• Piperacillin + Tazobactam is available as a freeze-dried powder that needs to be reconstituted and diluted before administration.

• It is administered intravenously only by a qualified healthcare professional, commonly in a hospital or healthcare facility setting.

Age and Dose Restrictions

• This medicine can be administered to adults, and children over the age of 2 months.

Contraindications

• This medicine is contraindicated in patients who have a history of severe allergic reactions to Piperacillin, Tazobactam, other penicillins, cephalosporins, or β-lactamase inhibitors.

Other Medications to Avoid with This Medicine

• Piperacillin + Tazobactam may interact with aminoglycoside antibiotics (such as gentamicin and amikacin) and anticoagulants (like warfarin and heparin).

Overdose and Missed Dose

• An overdose of this medicine may lead to severe side effects such as gastrointestinal upset or neurological symptoms. If you suspect an overdose, contact your doctor immediately.

• If you miss a dose, take it as soon as you remember. However, if it is close to the time for your next dose, skip the missed dose and continue your regular dosage schedule.

Management of Side Effects

Most side effects are temporary, generally harmless, and are resolved once this medicine is stopped. However, if you experience severe side effects or worsening symptoms, please consult your doctor.

• To avoid dehydration caused by diarrhoea or vomiting, ensure you drink plenty of fluids.

• Consuming bland, light meals can help manage nausea.

• Rest and relaxation techniques can aid in managing side effects like headaches or insomnia.

Use in Driving and Operating Machinery

• Piperacillin + Tazobactam does not typically affect your ability to drive or operate heavy machinery. However, if you feel unwell or experience side effects such as dizziness or fatigue, avoid these activities until you feel better.

Use in Pregnancy and Lactation

• Piperacillin + Tazobactam should be used in pregnancy only if your doctor determines that it is clearly needed, and the benefit outweighs the risk to the foetus.

• This medicine is passed into breast milk in low concentrations. Always consult your doctor if you are pregnant or breastfeeding before starting this medication.

Caution in Other Conditions

• Patients with kidney impairment should consult a doctor before using this medicine, as dosage adjustments may be necessary.

• Patients with a history of seizures, cystic fibrosis, gastrointestinal disorders like colitis, and cardiac diseases should also take this medicine with caution.

Special Dietary and Lifestyle Recommendation

• Maintain good hygiene to prevent recurrent infections.

• Get vaccinated regularly to boost immunity against infections.

• Avoid close contact with people who have infectious diseases.

• Drink plenty of fluids and maintain a balanced diet for overall health.

• Regular sleep and stress management techniques can support a healthy immune system.