Repaglinide

Dosage Forms Available

• Repaglinide can be taken orally (tablet).

Age and Dose Restrictions

• This medicine is intended for use in adults with type 2 diabetes mellitus.

Contraindications

• This medication is contraindicated in patients with type 1 diabetes mellitus and diabetic ketoacidosis. Repaglinide should not be used by individuals with known hypersensitivity to the active ingredient or any of the excipients. It is also contraindicated for patients with severe liver impairment.

Other Medications to Avoid

• Repaglinide may interact with strong CYP3A4 (like itraconazole, and clarithromycin), CYP2C8 inhibitors (like gemfibrozil) and CYP2C8 inducers (like rifampin, and carbamazepine).

Overdose and Missed Dose

• An overdose of Repaglinide can cause severe hypoglycaemia. If you suspect an overdose, consult a doctor immediately.

• If you miss a dose, skip that dose if the meal was missed. If an extra meal is eaten, take an additional dose. Do not double your dose to make up for the missed one.

Management of Side Effects

Most side effects are temporary and generally harmless and resolve when discontinuing this medicine. However, if you experience any severe side effects or worsening of any of the symptoms, please consult your doctor.

• Consuming small and frequent meals can manage the symptoms of hypoglycaemia.

• Drinking plenty of fluids may help manage diarrhoea.

Use in Driving and Operating Machinery

• Repaglinide may cause side effects that can affect your ability to drive or operate machinery, such as dizziness. Avoid driving or operating heavy machinery until you know how this medication affects you.

Use in Pregnancy and Lactation

• Consult your doctor if you are pregnant or breastfeeding before taking this medication.

Caution in Other Conditions

• Patients with moderate to severe renal impairment and mild to moderate hepatic impairment should exercise caution when taking Repaglinide. Individuals with hypersensitivity reactions should also be cautious while using this medication.

Special Dietary and Lifestyle Recommendations

• Regular monitoring of blood glucose levels is recommended for better disease management.

• Regular check-ups are advised to monitor the condition effectively.