Dapefy S 10100 Tablet 15

Dapefy S 10/100 Tablet 15

Sun Pharmaceutical Industries Ltd

Strip of 15 Units

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Composition

Dapagliflozin (10 Mg) + Sitagliptin (100 Mg)

Dapefy-S 10/100 Tablet is primarily used to manage type 2 diabetes mellitus in adults. It belongs to a class of medicines known as anti-diabetic medications, which are specifically designed combination medicines.

This medicine also helps enhance the effects of diet and exercise for better glycemic control. It is particularly beneficial for patients who have not responded adequately to metformin alone or those already using the individual components of this medicine.

This medicine should be taken orally, as your doctor directs. Before you start this medicine, make sure your doctor is aware of any pre-existing conditions or ongoing medications. If you experience any side effects, inform your doctor immediately. For best results, continue taking the medicine for the period prescribed by your doctor.

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Dapefy-S 10/100 Tablet is used for the following:

Assisting in the management of type 2 diabetes mellitus in adults
Complementing diet and exercise for better glycemic control
Beneficial for patients who have inadequate control with metformin alone
Useful for those already treated with dapagliflozin and sitagliptin individually

Directions for Use of Dapefy S 10/100 Tablet 15

Swallow the tablet whole with a glass of water.
Avoid crushing or chewing the tablet.
Do not alter the recommended dose without consulting your doctor.
Remember, it's crucial not to stop taking this medicine without speaking to your doctor first.

Dapefy-S 10/100 Tablet is taken orally.

Side Effects of Dapefy S 10/100 Tablet 15

Dapefy-S 10/100 Tablet may have the following common side effects:

Genital mycotic infections: This refers to fungal infections in the genital area.
Nasopharyngitis: This is an inflammation of the nose and throat, often causing symptoms like a runny nose and a sore throat.
Urinary tract infections
Upper respiratory tract infections
Headache
Back pain
Arthralgia: This means joint pain. It can occur anywhere in your body where two or more bones meet.
Nausea
Diarrhoea

Managing the Side Effects:

Most side effects are temporary and generally harmless, which resolve on discontinuing the use of Dapefy-S 10/100 Tablet. However, if you experience any serious side effects or worsening of any of the symptoms, please consult your doctor.

Here are some general guidelines for managing common side effects:

Diarrhoea: Consume plenty of water and healthy fluids to avoid dehydration.
Nausea: If you feel nauseated after taking this medicine, consider taking it after meals to lessen this effect.

Dapefy-S 10/100 Tablet comprises two key ingredients:

Dapagliflozin (10 mg): This component works in your body by inhibiting a protein called Sodium-Glucose Cotransporter 2 (SGLT2). This protein usually reabsorbs glucose from your urine back into the bloodstream. By blocking SGLT2, dapagliflozin increases glucose excretion through urine, which helps reduce blood glucose levels.
Sitagliptin (100 mg): Sitagliptin functions by inhibiting an enzyme called Dipeptidyl Peptidase-4 (DPP-4). This enzyme normally breaks down hormones called incretins, which include glucagon-like peptide-1 (GLP-1) and glucose-dependent insulinotropic polypeptide (GIP). By preventing the rapid breakdown of these hormones, sitagliptin increases their effects, contributing to a rise in insulin secretion and a decrease in glucagon secretion, both of which depend on glucose levels.

Pregnancy

Caution is advised while taking Dapefy-S 10/100 Tablet if you are pregnant. It is best to consult your doctor before taking this medicine.

Breastfeeding

The effect of Dapefy-S 10/100 Tablet on breastfeeding mothers is not known. You should consult your doctor to understand the potential risks and benefits.

Alcohol

There is no specific information about consuming alcohol while taking Dapefy-S 10/100 Tablet. However, it's always a good idea to discuss this with your doctor.

Liver

If you have liver problems, discuss them with your doctor before starting Dapefy-S 10/100 Tablet. This medicine may affect liver function.

Kidney

Caution is advised before using Dapefy-S 10/100 Tablet if you have a history of any kidney problems. It is a good idea to consult your doctor before taking this medicine.

Using Machines & Driving

There is no specific information about the effects of Dapefy-S 10/100 Tablet on the ability to drive or operate machinery. As a precaution, it's best to avoid doing so until you know how the medicine affects you.

Allergy

If you are allergic to dapagliflozin or sitagliptin, which are the active ingredients in Dapefy-S 10/100 Tablet, or any other ingredients in the tablet, do not take this medicine. Always check with your doctor first.

Children

The safety and effectiveness of Dapefy-S 10/100 Tablet in children have not been established. Always consult your doctor before giving this medicine to a child.

Older Patients

Older patients should take Dapefy-S 10/100 Tablet under medical supervision as they may be more susceptible to its side effects. Caution is advised if patients are above 70 years of age. Your doctor will guide you based on your health status.

Interactions of Dapefy S 10/100 Tablet 15

Drug-Drug Interactions

Dapefy-S 10/100 Tablet interacts with the following medicines:

Insulin and insulin secretagogues: When combined with Dapefy-S 10/100 Tablet, medicines like insulin or glimepiride can increase the risk of hypoglycaemia (low blood sugar). It may require a lower dose of insulin or an insulin secretagogue.
Diuretics: Medicines like furosemide or hydrochlorothiazide, when taken with Dapefy-S 10/100 Tablet, may enhance the risk of volume depletion and symptomatic hypotension (low blood pressure).
Heart medications: Heart medicines like digoxin may have slightly increased plasma concentrations when taken with Dapefy-S 10/100 Tablet. Monitoring is required for patients on digoxin.

Drug-Food Interactions

No specific food interactions have been reported with Dapefy-S 10/100 Tablet.

Drug-Disease Interactions

Dapefy-S 10/100 Tablet interacts with the following diseases:

Renal impairment: Patients with moderate to severe kidney impairment or end-stage kidney disease should not take Dapefy-S 10/100 Tablet due to increased risk of adverse effects.
Hypotension: Individuals with low blood pressure need to be cautious as Dapefy-S 10/100 Tablet can cause volume depletion leading to symptomatic hypotension.
Ketoacidosis: People prone to ketoacidosis, a serious condition causing high levels of ketones in the body, should be monitored closely while taking this medication.

Daily Dose

The daily dose of Dapefy-S 10/100 Tablet should be taken as prescribed by your doctor. The dosage could vary based on individual factors such as the severity of your condition and how well you respond to treatment. Always follow the prescribed dosage and don't exceed it without consulting your doctor.

Over Dose

If you accidentally take more Dapefy-S 10/100 Tablets than you were prescribed, you might experience symptoms like nausea, headache, and dizziness. If you experience these or any other symptoms, inform your doctor right away.

Missed Dose

If you forget to take your scheduled dose of Dapefy-S 10/100 Tablet, take it as soon as you remember. If it's nearly time for your next dose, skip the one you missed and continue with your regular schedule. Don't increase your dosage without consulting your doctor.

Store Dapefy-S 10/100 Tablet in a closed container at room temperature, ideally below 30°C.
Keep it away from excessive heat, light, and moisture.
Ensure that the medicine is kept out of reach of children.
Always use Dapefy-S 10/100 Tablet before its expiry date.

Consuming a balanced diet with a focus on fruits, vegetables, lean proteins, and whole grains can support your body's response to this medicine for managing type 2 diabetes.
Regular physical activity is vital. Aim for at least 30 minutes of moderate exercise like walking or cycling daily, as it helps lower blood glucose levels. Remember to consult your doctor before starting any new exercise regime.

Fact Box

Drug Category	SGLT2 Inhibitor, DPP-4 Inhibitor
Therapeutic Category	Antidiabetic
Available Dosage Types	Tablet
Habit Forming	No
Ailment	Type 2 Diabetes Mellitus

What is Dapefy-S 10/100 Tablet used for?

Dapefy-S 10/100 Tablet is primarily used to manage type 2 diabetes in adults, when diet and exercise alone aren't enough.

How does Dapefy-S 10/100 Tablet work?

This medicine contains two active ingredients - dapagliflozin and sitagliptin, which work together to help control your blood sugar levels effectively.

Can Dapefy-S 10/100 Tablet be taken on an empty stomach?

Consume plenty of water and healthy fluids to avoid dehydration.

Who should not take Dapefy-S 10/100 Tablet?

People with type 1 diabetes, diabetic ketoacidosis, severe kidney problems, or those allergic to any of the components shouldn't take this medicine.

What are the possible side effects of Dapefy-S 10/100 Tablet?

Some common side effects include urinary tract infections, nasal congestion (nasopharyngitis), headaches and back pain. More serious side effects are rare but possible.

Can I take Dapefy-S 10/100 Tablet if I'm pregnant or breastfeeding?

The safety of this medicine during pregnancy or breastfeeding has not been established. Consult your doctor if you are pregnant or nursing.

Is it safe to drive after taking Dapefy-S 10/100 Tablet?

As long as you do not experience dizziness or low blood sugar (hypoglycemia) after taking this medicine, it should be safe to drive.

Last Updated On 23 Dec. 2024 | 10:53AM (IST)

Certified Content

Written by

Dr Nikita Lobo

Medical Editor & Reviewer | 7 years

BDS, MDS

Reviewed by

Dr. Chhavi Rosha

Health & Medical Content Writer | 8 years

BMS, FMC, MD Resident

Check out Editorial Policy

Manufacturer details

SCO No. 14, Sector 5, Panchkula – 134114, Haryana

Country of origin: INDIA

References

AstraZeneca. (2014). HIGHLIGHTS OF PRESCRIBING INFORMATION [Press release]. https://www.accessdata.fda.gov/drugsatfda_docs/label/2020/202293s020lbl.pdf
Dapagliflozin: Uses, interactions, mechanism of action | DrugBank Online. (n.d.). DrugBank. https://go.drugbank.com/drugs/DB06292
Merck Sharp & Dohme Corp. (2006). Highlights of prescribing information [Press release]. https://www.accessdata.fda.gov/drugsatfda_docs/label/2012/021995s019lbl.pdf
Sitagliptin: Uses, interactions, mechanism of action | DrugBank Online. (n.d.). DrugBank. https://go.drugbank.com/drugs/DB01261

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We, at Truemeds make a diligent attempt to deliver accurate, expert- drafted and thoroughly reviewed medicine related information to our consumers. However, it should, by no means, be considered a substitute for prescription from a certified doctor or a trustworthy doctor-patient relationship. In fact we detest any form of self medication without expert advice. The sole purpose of the information on our portal is to educate our consumers, which helps improve the communication between a doctor and a patient. The information by no means is complete in its entirety and should not be used to diagnose or treat any medical condition. No amount of information can replace the experience and expertise of a doctor, therefore his/her advice always holds priority and should be followed appropriately.

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