Geminor M2 Forte Tablet 15

Macleods Pharmaceuticals Pvt.ltd

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Composition

Glimepiride (2 Mg) + Metformin (1000 Mg)

Geminor M2 Forte Tablet is used to manage type 2 diabetes mellitus in adults, particularly when diet, exercise, and monotherapy with glimepiride or metformin are insufficient to control blood sugar levels. This combination medicine belongs to the class of oral antidiabetic medications.

In addition to its main function, the medicine also assists in improving insulin sensitivity and reducing hepatic glucose production. By doing so, it helps in achieving better glycemic control when the effectiveness of individual constituents, glimepiride or metformin, is not sufficient.

Before starting this medication, it's crucial to consult your doctor who will determine the appropriate dosage and frequency best suited for your condition. Inform your doctor about any pre-existing conditions or ongoing medications. If you experience any side effects while on this medicine, alert your doctor promptly. For optimal results, continue taking this medicine for the duration prescribed by your doctor.

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Geminor M2 Forte Tablet is used for the following:

Management of type 2 diabetes mellitus in adults
Improvement of blood sugar control when diet and exercise alone are insufficient
Enhancement of glycemic regulation when a single medicine is inadequate.

Here are some instructions on how to take Geminor M2 Forte Tablet:

Swallow the tablet whole with a glass of water.
Do not chew or crush the tablet.
Take this medicine preferably with your evening meal.
It's crucial not to stop taking this medicine without consulting your doctor first.

Geminor M2 Forte Tablet is taken orally.

Geminor M2 Forte Tablet may have the following common side effects:

Hypoglycaemia: This is when your blood sugar drops too low. You might feel dizzy, sweaty, or shaky.
Diarrhoea
Nausea
Abdominal pain: This refers to pain in your stomach area.
Headache
Flatulence: This means having excess gas in your stomach or intestines, which can lead to bloating or belching.

Managing the Side Effects:

Most side effects are temporary and generally harmless, which resolve upon discontinuing the use of Geminor M2 Forte Tablet. However, if you experience any serious side effects or worsening of any symptoms, please consult your doctor. Here are some tips for managing common side effects:

Hypoglycaemia: Keep a small snack handy to eat if you feel symptoms of low blood sugar.
Diarrhoea: Try taking Geminor M2 Forte Tablet with your evening meal to lessen this effect.

Geminor M2 Forte Tablet consists of two active ingredients that work together in managing high blood sugar levels:

Metformin (1000 mg): This ingredient belongs to the biguanide class of antidiabetic medicines. It works by reducing the amount of glucose produced by the liver, decreasing the absorption of glucose from the gut, and enhancing the body's response to insulin. It does this by activating a specific liver enzyme that plays a central role in insulin signalling, energy balance, and the metabolism of glucose and lipids.
Glimepiride (2 mg): This component belongs to a class of medications known as sulfonylureas. It stimulates insulin secretion from the pancreatic beta cells. By binding to certain receptors on the cell membrane, it causes these cells to release insulin, a hormone that helps cells take in glucose from the blood.

Pregnancy

Geminor M2 Forte Tablet falls under Category C for pregnancy. This means there is a potential risk to the foetus. It's best to consult your doctor if you are pregnant or planning to conceive.

Breastfeeding

The active ingredients, metformin and glimepiride, are found in human milk. As the effects on the breastfeeding infant are unknown, it's advised not to take this medicine while lactating.

Alcohol

Alcohol may increase the risk of lactic acidosis, a rare but serious complication associated with metformin. Caution is advised when drinking alcohol while taking this medicine.

Liver

The liver plays a key role in metabolising glimepiride, which is one of the constituents of Geminor M2 Forte Tablet. If you have liver health issues, it's best to consult your doctor before starting this medication.

Kidney

Metformin, component of Geminor M2 Forte Tablet, is excreted unchanged in urine. Therefore, if you have kidney problems, it is best to discuss them with your doctor before starting this medicine.

Using Machines & Driving

No specific precautions exist regarding using machines or driving while taking this medicine. However, always ensure you know how your body reacts to Geminor M2 Forte Tablet before operating machinery or driving.

Allergy

If you have known hypersensitivity to glimepiride or metformin or any other component in this medicine, avoid taking Geminor M2 Forte Tablet.

Children

The safety and effectiveness of Geminor M2 Forte Tablet in children have not been established yet. Always consult your doctor before giving any medicine to a child.

Older Patients

Elderly patients are more likely to have decreased kidney function, which could affect the excretion of metformin. Dose selection for elderly patients should be cautious, usually starting at the low end of the dosing range. Monitoring of renal function is recommended while taking this medicine.

Drug-Drug Interactions

Geminor M2 Forte Tablet interacts with the following medicines:

Contrast agents: These can impair renal function, leading to an increase in metformin levels and risk of lactic acidosis. Examples include iodixanol and iohexol.
NSAIDs: NSAIDs such as ibuprofen and diclofenac may impair renal function, increasing metformin levels and the risk of lactic acidosis.
Other antidiabetic agents: When used alongside other antidiabetic medicines like insulin or glibenclamide, glimepiride in Geminor M2 Forte Tablet may increase the risk of hypoglycemia.
Beta-blockers: Medicines like propranolol or atenolol may mask the signs of hypoglycemia caused by glimepiride.
Corticosteroids: These medicines including prednisone and dexamethasone can lead to hyperglycemia, compromising glycemic control.
Oral contraceptives: Estrogen-containing contraceptives can also cause hyperglycemia, affecting glycemic control.

Drug-Food Interactions

Certain foods can interact with Geminor M2 Forte Tablet. Here are some examples:

High-fibre foods: Foods high in fibre may decrease the absorption of metformin, reducing its effectiveness.

Drug-Disease Interactions

Geminor M2 Forte Tablet interacts with the following diseases:

Severe renal impairment: In patients with severe renal impairment (eGFR below 30 mL/min/1.73m2), metformin accumulation could occur, increasing the risk of lactic acidosis.
Congestive heart failure: If you have this condition requiring pharmacologic treatment, Geminor M2 Forte Tablet may not be suitable for you.
Metabolic acidosis: In acute or chronic metabolic acidosis, including diabetic ketoacidosis, Geminor M2 Forte Tablet should not be used.
Hypoxic states: Conditions that reduce oxygen supply to tissues can increase the risk of lactic acidosis with metformin.

Daily Dose

Your doctor will prescribe the daily dose of Geminor M2 Forte Tablet. This may vary based on your condition and response to treatment. Always follow the prescribed dosage.

Over Dose

If you accidentally take more than the prescribed dose of Geminor M2 Forte Tablet, you may experience symptoms like nausea, abdominal pain, and discomfort. Inform your doctor about this.

Missed Dose

If you forget to take your Geminor M2 Forte Tablet, take it as soon as you remember. If it's nearly time for the next dose, skip the missed one.

Store your Geminor M2 Forte Tablet at room temperature.
Keep it away from direct light and moisture.
Always keep the medicine out of reach of children.
Remember to use the tablet before its expiry date.

Maintain a balanced diet with low sugar content. Reducing sugar intake can help manage your blood glucose levels.
Regular physical activity is also key. A daily exercise routine assists in controlling blood sugar levels, making the Geminor M2 Forte Tablet more effective.

Fact Box

Available Dosage Types	Tablet
Habit Forming	No
Ailment	Type 2 Diabetes Mellitus
Drug Category	Biguanide, Sulfonylurea
Therapeutic Category	Antidiabetic

What is Geminor M2 Forte Tablet used for?

Geminor M2 Forte Tablet is used to manage type 2 diabetes in adults, alongside diet and exercise when other medicines alone have not controlled blood sugar levels effectively.

How does Geminor M2 Forte Tablet work?

The medicine works by combining two active ingredients: metformin, which helps the body to use insulin more efficiently and reduces glucose production, and glimepiride, which boosts insulin production.

Can Geminor M2 Forte Tablet cause side effects?

Yes, possible side effects include low blood sugar (hypoglycaemia), diarrhoea, nausea, abdominal pain, headache, and bloating. In rare cases, it may cause lactic acidosis.

Can I take this medicine if I am pregnant or breastfeeding?

Geminor M2 Forte Tablet should be taken during pregnancy only if the potential benefit justifies the potential risk to the baby. It should not be taken while breastfeeding.

Are there any precautions I need to take while on this medication?

Yes, you should monitor your blood sugar regularly and avoid excessive alcohol consumption as it can increase the risk of lactic acidosis. Regular monitoring of Vitamin B12 levels is also advised.

What should I do if I take too much of this medication?

Overdosage can lead to low blood sugar (hypoglycaemia) and lactic acidosis. If you think you've taken too much, seek immediate medical help.

Can Geminor M2 Forte Tablet interact with other medicines?

Yes, certain medicines like contrast agents and NSAIDs can affect how well Geminor M2 Forte Tablet works or increase the risk of side effects. Always consult your doctor before starting any new medicine.

Last Updated On 11 Aug. 2025 | 7:41AM (IST)

Certified Content

Written by

Dr Nikita Lobo

Medical Content Reviewer | 8 years

BDS, MDS

Reviewed by

Dr. Chhavi Rosha

Medical Content Writer | 9 years

BAMS, FMC, MD Resident

Check out Editorial Policy

Manufacturer details

Atlanta Arcade, Marol Church Rd, Bori Colony, Vijay Nagar Colony West, Marol, Andheri East, Mumbai, Maharashtra 400059

Country of origin: INDIA

Expiry on or after: February 2026

In case of any issues, contact us:

support@truemeds.in|09240250346

Address: 6th floor, Urmi Corporate Park Solaris, Saki Vihar Road, Andheri East, Mumbai 400071

References

Unknown. (2022). GLUCOPHAGE. https://www.accessdata.fda.gov/drugsatfda_docs/label/2017/020357s037s039,021202s021s023lbl.pdf
AMARYL. (n.d.). AMARYL (glimepiride tablets) 1, 2, and 4 mg. https://www.accessdata.fda.gov/drugsatfda_docs/label/2009/020496s021lbl.pdf
Metformin: Uses, interactions, mechanism of action | DrugBank Online. (n.d.). DrugBank. https://go.drugbank.com/drugs/DB00331
Glimepiride: Uses, interactions, mechanism of action | DrugBank Online. (n.d.). DrugBank. https://go.drugbank.com/drugs/DB00222

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Disclaimer

We, at Truemeds make a diligent attempt to deliver accurate, expert- drafted and thoroughly reviewed medicine related information to our consumers. However, it should, by no means, be considered a substitute for prescription from a certified doctor or a trustworthy doctor-patient relationship. In fact we detest any form of self medication without expert advice. The sole purpose of the information on our portal is to educate our consumers, which helps improve the communication between a doctor and a patient. The information by no means is complete in its entirety and should not be used to diagnose or treat any medical condition. No amount of information can replace the experience and expertise of a doctor, therefore his/her advice always holds priority and should be followed appropriately.

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