Gliclanux Xr 60 Tablet 10

Nicholas Healthcare Limited

Strip of 10 Units

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Composition

Gliclazide (60 Mg)

Gliclanux Xr 60 Tablet 10 is primarily used to manage type 2 diabetes mellitus in adults. It belongs to the class of oral sulfonylurea antidiabetic agents, which stimulate the pancreas to secrete more insulin.

In addition to its primary use, it helps maintain stable blood sugar levels throughout the day. This can prevent serious complications associated with diabetes and promote overall health when used alongside a balanced diet, regular exercise, and frequent blood sugar monitoring.

Before starting this medication, consult your doctor for the correct dosage and frequency. Inform your doctor of any pre-existing health conditions or other medications you are taking. If you experience any side effects while using this medicine, notify your doctor immediately. Continue taking the medication for the full duration prescribed by your doctor to achieve the best results.

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Gliclanux Xr 60 Tablet 10 is used for the management of Type 2 diabetes mellitus.

Directions for Use of Gliclanux Xr 60 Tablet 10

Take this medicine orally with a glass of water.
Do not chew or crush the tablet, swallow it whole.
Always take this medication as advised by your doctor.

Gliclanux Xr 60 Tablet 10 is taken orally.

Side Effects of Gliclanux Xr 60 Tablet 10

While taking Gliclanux Xr 60 Tablet 10, you might experience some common side effects, including:

Upper respiratory tract infection
Headache
Nausea
Diarrhoea
Dizziness
Hypoglycaemia: This is when your blood sugar levels fall too low, causing symptoms like shakiness, hunger, and dizziness.
Arthralgia: This means pain in the joints.
Edema: This refers to swelling caused by fluid trapped in your body's tissues.

Managing the Side Effects:

Most side effects are temporary and generally harmless, which resolve on discontinuing the use of Gliclanux Xr 60 Tablet 10. However, if you experience any serious side effects or worsening of any of the symptoms, please consult your doctor.

Here are a couple of tips to manage common side effects:

Hypoglycaemia: If you feel dizzy, try having a small snack or drink containing sugar.
Diarrhoea: Try taking Gliclanux Xr 60 Tablet 10 with food to reduce this effect.

Gliclanux Xr 60 Tablet 10 contains gliclazide (60 mg), which works on the body in several ways:

Insulin secretion: Gliclazide stimulates the release of insulin from functioning pancreatic beta cells.
Insulin sensitivity: It enhances the sensitivity of target tissues like muscle, fat, and liver to insulin. This means these tissues are better able to absorb and use glucose from the blood.
Glucose output: Gliclazide suppresses the production of glucose in the liver.
Carbohydrate absorption: It slows down the absorption of carbohydrates from your intestine after meals.

Pregnancy

Using Gliclanux Xr 60 Tablet 10 when you're pregnant is not recommended. It's best to consult your doctor before taking this medicine.

Breastfeeding

If you are breastfeeding, it is not known whether gliclazide passes into breast milk. It's safer to discontinue nursing or medicine during this period.

Alcohol

Be cautious with alcohol intake while on this medication, as it may increase the risk of low blood sugar (hypoglycaemia).

Liver

For those with liver health issues, the use of Gliclanux Xr 60 Tablet 10 should be initiated conservatively at the lower end of the dosing range. Your doctor will guide you based on your health status.

Kidney

If you have kidney problems, caution is advised when taking Gliclanux Xr 60 Tablet 10. Dosage adjustments may be necessary, as clearance can be reduced in patients with renal impairment.

Using Machines & Driving

Gliclanux Xr 60 Tablet 10 might cause dizziness or blurred vision in some individuals. Don't drive or operate machinery if you experience these symptoms.

Allergy

If you have known allergies to gliclazide, other sulfonylureas, sulfonamides, or any other components of Gliclanux Xr 60 Tablet 10, avoid using this medicine.

Children

The safety and effectiveness of Gliclanux Xr 60 Tablet 10 have not been well-established in children. Therefore, be cautious when giving it to individuals under 18 years of age. Consult your paediatrician before giving any medicine to children.

Older Patients

Older patients might be more susceptible to the side effects of Gliclanux Xr 60 Tablet 10, including low blood sugar levels (hypoglycaemia). Such patients should start at the lower end of the dosing range strictly under medical supervision.

Interactions of Gliclanux Xr 60 Tablet 10

Drug-Drug Interactions

Gliclanux Xr 60 Tablet 10 interacts with the following medicines:

Beta-blockers: Medications such as propranolol and metoprolol can enhance the blood sugar-lowering effect of Gliclanux Xr 60 Tablet 10, potentially leading to hypoglycaemia (low blood sugar levels).
ACE inhibitors: Medications like lisinopril and enalapril can increase the hypoglycaemic effect of Gliclanux Xr 60 Tablet 10.
Thiazides: Diuretics such as hydrochlorothiazide can diminish the blood sugar-lowering effect of Gliclanux Xr 60 Tablet 10.
Corticosteroids: Medications like prednisone and dexamethasone can reduce the hypoglycaemic effect of Gliclanux Xr 60 Tablet 10.
Antifungal medications: Medicines like miconazole can cause severe hypoglycaemia when taken with Gliclanux Xr 60 Tablet 10.
Cholesterol-lowering medicines: Medications like colesevelam may decrease the absorption of gliclazide when used alongside Gliclanux Xr 60 Tablet 10.

Drug-Food Interactions

Certain foods may interact with Gliclanux Xr 60 Tablet 10. Details are as follows:

High-fibre foods: Foods high in fibre may slow down the absorption of gliclazide, potentially reducing its effectiveness.

Drug-Disease Interactions

Gliclanux Xr 60 Tablet 10 interacts with the following diseases:

Liver disease: This medication is metabolised in the liver; thus, patients with liver disease should use it cautiously as it could exacerbate their condition.
Renal impairment: Gliclazide is excreted through the kidneys. Therefore, in patients with kidney disease, the clearance of gliclazide may be reduced, potentially leading to hypoglycaemia.
Glucose-6-phosphate dehydrogenase (G6PD) deficiency: Gliclanux Xr 60 Tablet 10 can cause hemolytic anaemia in patients with G6PD deficiency.

Daily Dose

Your doctor will prescribe the daily dose of Gliclanux Xr 60 Tablet 10 depending on factors like your condition's severity and how you respond to the medicine. Make sure to adhere to the prescribed dosage and avoid exceeding it without consulting your doctor.

Over Dose

If you accidentally take more Gliclanux Xr 60 Tablet 10 than prescribed, you may experience symptoms such as tremors, increased appetite, and sweating, which are signs of hypoglycaemia (low blood sugar). If you notice these symptoms or if they worsen, inform your doctor immediately.

Missed Dose

If you forget to take a dose of Gliclanux Xr 60 Tablet 10, take it as soon as you remember. However, if it's almost time for your next dose, skip the missed one and continue with your regular schedule. Never alter your dosage without consulting your doctor.

Store your Gliclanux Xr 60 Tablet 10 in a tightly closed container.
Keep in a dark, dry place.
Keep it out of reach and sight of children.

Incorporate a balanced diet rich in whole grains, fruits, and vegetables into your daily routine. This can aid in controlling blood sugar levels alongside the use of Gliclanux Xr 60 Tablet 10.
Engage in regular physical activities, such as walking or cycling. This helps improve insulin sensitivity, which is beneficial for managing type 2 diabetes mellitus.

Fact Box

Drug Category	Sulfonylurea Antidiabetic
Therapeutic Category	Oral Hypoglycemic
Available Dosage Types	Tablet
Habit Forming	No
Ailment	Type 2 Diabetes Mellitus

What is Gliclanux Xr 60 Tablet 10 used for?

Gliclanux Xr 60 Tablet 10 is a medicine used to manage type 2 diabetes in adults, helping to control blood sugar levels.

How does Gliclanux Xr 60 Tablet 10 work?

The active ingredient, gliclazide, stimulates insulin secretion and improves insulin sensitivity, managing blood sugar levels effectively.

Is Gliclanux Xr 60 Tablet 10 safe for everyone?

No, it's not suitable for patients with type 1 diabetes, diabetic ketoacidosis, or allergies to sulfonylureas, sulfonamides, or any of the excipients.

Can Gliclanux Xr 60 Tablet 10 cause hypoglycaemia?

Yes, gliclazide can cause hypoglycaemia (low blood sugar), especially in elderly or malnourished patients and those with liver or kidney problems.

Can I take other medicines while on Gliclanux Xr 60 Tablet 10?

Some medicines, like thiazides, may interact with gliclazide and affect its function. Always consult your doctor before starting any new medicine.

Is it safe to take Gliclanux Xr 60 Tablet 10 during pregnancy?

Gliclazide is not recommended during pregnancy unless prescribed by your doctor. If you're pregnant or planning to be, consult your doctor about alternatives.

What should I do if I overdose on Gliclanux Xr 60 Tablet 10?

Overdosing may lead to severe hypoglycaemia. Seek immediate medical help if you've taken more than the recommended dose.

Certified Content

Written by

Dr. Michelle Frank

Medical Content Writer | 8 years

Doctor of Medicine

Reviewed by

Dr. Divya Chauhan

Medical Writer & Reviewer | 6 years

BAMS, APG, PG

Check out Editorial Policy

Manufacturer details

503/504 Hubtown solaris, Andheri (E), Mumbai 400069 INDIA

Country of origin: INDIA

References

National Center for Biotechnology Information (2024). PubChem Compound Summary for CID 3475, Gliclazide. Retrieved August 12, 2024 from https://pubchem.ncbi.nlm.nih.gov/compound/Gliclazide.
National Health Service. (2021). Gliclazide [Internet]. NHS. https://www.nhs.uk/medicines/gliclazide/
Ishibashi F, Takashina S. (1990, March) The effect of timing on gliclazide absorption and action. Hiroshima J Med Sci. 39(1):7-9. https://pubmed.ncbi.nlm.nih.gov/2373640/
Gliclazide. (2024, 5). Diabetes UK. https://www.diabetes.org.uk/guide-to-diabetes/managing-your-diabetes/treating-your-diabetes/tablets-and-medication/sulphonylureas/gliclazide
Drouin P, Standl E; Diamicron MR Study Group. (2004, November). Gliclazide modified release: results of a 2-year study in patients with type 2 diabetes. Diabetes Obes Metab. 6(6):414-21. https://pubmed.ncbi.nlm.nih.gov/15479217/

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