Istamet D Xr 1000 Tablet 7

Istamet D-XR 1000 Tablet is recommended for the following:

• Management of blood sugar levels in adults with type 2 diabetes

• Assisting in the reduction of the risk of hospitalisation due to heart failure among patients with type 2 diabetes and established cardiovascular disease or multiple cardiovascular risk factors.

To use Istamet D-XR 1000 Tablet correctly, please follow these instructions:

• Swallow the tablet whole with a glass of water.

• Do not crush, cut or chew the tablet.

• Take this medicine once daily with your evening meal.

• Do not take more than the recommended dose without consulting your doctor.

• It's important not to stop taking this medicine without speaking to your doctor first.

Istamet D-XR 1000 Tablet is taken orally.

The Istamet D-XR 1000 Tablet has three active ingredients each performing a unique role:

• Dapagliflozin (10 mg): This ingredient works as a sodium-glucose cotransporter-2 (SGLT2) inhibitor. By reducing renal glucose reabsorption, it increases urinary glucose excretion leading to lowered blood sugar levels. It also helps in decreasing blood pressure and body weight.

• Metformin (1000 mg): Classified as a biguanide, metformin's function is threefold. It decreases hepatic glucose production, reduces intestinal glucose absorption and enhances insulin sensitivity by increasing peripheral glucose uptake and utilisation.

• Sitagliptin (100 mg): As a dipeptidyl peptidase-4 (DPP-4) inhibitor, sitagliptin slows down the inactivation of incretin hormones. This leads to an increase in insulin synthesis and release from pancreatic beta cells while suppressing glucagon secretion from pancreatic alpha cells.

• Keep Istamet D-XR 1000 Tablet in a dry place protected from light.

• Store at a temperature between 20°C and 25°C, with short periods allowed between 15°C and 30°C.

• Ensure this medicine is out of reach of children.

• Always use it before the expiry date printed on the pack.

• As Istamet D-XR 1000 Tablet is used to manage type 2 diabetes, you should follow a balanced diet low in sugars. This can help control your blood sugar levels effectively.

• Regular physical exercise like walking or cycling can further aid in keeping your blood sugar levels in check. Remember to consult your doctor about the suitable type and intensity of exercise for you.