Semi Daonil 25 Mg Tablet 10

Semi Daonil Tablet 10

Emcure Pharmaceuticals Ltd

Strip of 10 Units

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MRP ~~₹7.38~~

₹6.05

₹0.74/Units

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Store Below 30^o C

Composition

Glibenclamide (2.5 Mg)

Semi-Daonil Tablet is a medicine primarily used to manage type 2 diabetes mellitus in adults. This medicine is part of the sulfonylureas group of antidiabetic medications.

This medicine can also be used as part of a comprehensive diabetes management plan. It is particularly helpful when diet, physical exercise, and weight reduction alone haven't been able to control blood glucose levels effectively.

You should take this medicine orally as directed by your doctor. Before you start, it's important to inform your doctor about any pre-existing conditions or ongoing medications. If you notice any side effects while on this medicine, let your doctor know immediately. To get the best results, continue taking the medicine for the duration prescribed by your doctor.

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Semi-Daonil Tablet is used to manage type 2 diabetes mellitus in adults

Directions for Use of Semi Daonil Tablet 10

Swallow the tablet whole with a glass of water without crushing or chewing it.
Do not exceed the recommended dose without consulting your doctor.

Semi-Daonil Tablet is taken orally.

Semi-Daonil Tablet may have the following side effects:

Hypoglycaemia: This refers to unusually low levels of blood sugar, which might result in symptoms like confusion, rapid heartbeat, shakiness, and sweating.
Headache
Dizziness
Nausea
Vomiting
Weight gain
Abdominal pain
Diarrhoea
Constipation

Managing the Side Effects:

Most side effects are temporary and generally harmless, which are resolved by discontinuing the use of Semi-Daonil Tablet. However, if you experience any serious side effects or worsening of any of the symptoms, please consult your doctor. Here are some general guidelines for managing common side effects:

Hypoglycaemia: Always have a source of glucose handy to manage sudden drops in blood sugar levels.
Nausea/Vomiting: Try taking Semi-Daonil Tablet with food or milk to reduce these effects.

Semi-Daonil Tablet contains glibenclamide (2.5 mg) and works on the body in the following ways:

Stimulates Insulin Secretion: Glibenclamide stimulates the pancreas to release more insulin. This happens because glibenclamide blocks ATP-sensitive potassium channels on pancreatic beta cells. Pancreatic beta cells are responsible for producing insulin in our body.
Enhances Insulin Sensitivity: Apart from stimulating insulin secretion, glibenclamide also increases the sensitivity of peripheral tissues to insulin. This process enhances the uptake and utilization of glucose by body tissues, helping to manage blood glucose levels effectively.

Pregnancy

Semi-Daonil Tablet is not recommended during pregnancy. If you are pregnant or planning to conceive, it's important to discuss this with your doctor before starting this medicine.

Breastfeeding

This medicine is not advised for breastfeeding women. Consult your doctor about potential risks and benefits.

Alcohol

Avoid consuming alcohol while taking Semi-Daonil Tablet, as it can intensify the medicine's blood sugar-lowering effect.

Liver

If you have liver problems, caution is needed when taking Semi-Daonil Tablet. As this medication may affect liver function, discuss your health status with your doctor before starting treatment.

Kidney

Caution is advised when using Semi-Daonil Tablet if you have a history of kidney problems. Make sure to consult your doctor before taking this medication.

Using Machines & Driving

Semi-Daonil Tablet may cause dizziness or confusion as side effects, which could affect your ability to drive or operate machinery. It's best to avoid such activities until you know how the medication affects you.

Allergy

Do not take Semi-Daonil Tablet if you are allergic to glibenclamide or any other ingredients in the formulation. Consult your doctor for alternative medications if necessary.

Children

Semi-Daonil Tablet is not recommended for children under 18 years of age. Always consult your doctor before giving any medicine to a child.

Older Patients

Older patients should take Semi-Daonil Tablet under medical supervision as they may be more susceptible to its side effects, particularly hypoglycemia (low blood sugar). Caution is advised if patients are over 70 years of age. Your doctor will guide you based on your health status.

Drug-Drug Interactions

Semi-Daonil Tablet interacts with the following medicines:

Beta-blockers: Medicines like propranolol or metoprolol may potentially increase the risk of low blood sugar or hypoglycemia when taken with Semi-Daonil Tablet.
Corticosteroids: Medications such as prednisone or cortisone may reduce the blood sugar-lowering effect of Semi-Daonil Tablet.
Thiazide diuretics: Medicines like hydrochlorothiazide can decrease the effect of Semi-Daonil Tablet on reducing blood glucose levels.
Thyroid medications: Thyroid medication such as levothyroxine may antagonise the glucose-lowering effect of Semi-Daonil Tablet.
Oral contraceptives: Birth control pills like ethinyl estradiol or norethindrone may decrease the efficacy of Semi-Daonil Tablet in managing blood sugar levels.

Drug-Food Interactions

Drug-Disease Interactions

Semi-Daonil Tablet interacts with the following diseases:

G6PD deficiency: People with this genetic disorder should use Semi-Daonil Tablet cautiously as it might increase the risk of haemolytic anaemia.
Adrenal or Pituitary insufficiency: These conditions could enhance the risk of hypoglycaemia with Semi-Daonil Tablet use.

Daily Dose

The daily dose of Semi-Daonil Tablet should be taken as advised by your doctor. The dosage may vary according to your individual health status and response to the medication. You must stick to the prescribed dosage and avoid making any changes without discussing it with your doctor.

Over Dose

In case of a suspected Semi-Daonil Tablet overdose, you might experience symptoms like severe low blood sugar, confusion, or excessive sweating. If such symptoms persist or worsen, inform your doctor promptly.

Missed Dose

If you forget to take your Semi-Daonil Tablet, take it as soon as you remember. However, if it is nearly time for your next dose, skip the missed one and continue with your regular schedule. Never double up on doses to compensate for a missed dose without consulting your doctor.

Store Semi-Daonil Tablet in a cool, dry place where the temperature stays below 30°C.
Keep it away from direct sunlight and moisture to maintain its efficacy.
Always ensure the medicine remains out of reach and sight of children.
Remember to use Semi-Daonil Tablet before its expiry date for optimal results.

Minimise your intake of sugars and refined carbohydrates. These foods can spike your blood sugar levels, which Semi-Daonil Tablet is working to manage.
Regular physical activity is key. A routine of moderate exercise can help improve your body's sensitivity to insulin, assisting the action of Semi-Daonil Tablet in managing your blood sugar levels.

Fact Box

Drug Category	Insulin Secretagogue
Therapeutic Category	Antidiabetic
Available Dosage Types	Tablet
Habit Forming	No
Ailment	Type 2 Diabetes Mellitus

What is Semi-Daonil Tablet used for?

Semi-Daonil Tablet is used to manage type 2 diabetes in adults when diet, exercise and weight reduction alone aren't enough to control blood sugar levels.

How does Semi-Daonil Tablet work?

The active ingredient in Semi-Daonil Tablet, glibenclamide, stimulates the pancreas to release more insulin, helping lower blood glucose levels.

Are there any side effects of taking Semi-Daonil Tablet?

Common side effects include low blood sugar, headache, dizziness, nausea, vomiting, weight gain and gastrointestinal disturbances such as abdominal pain and diarrhoea.

Who should not take Semi-Daonil Tablet?

Individuals with type 1 diabetes, severe kidney or liver problems, or a known allergy to glibenclamide should not take this medicine. Consult your doctor for advice.

Can Semi-Daonil Tablet interact with other medicines?

Yes. Semi-Daonil Tablet can interact with several medications such as beta-blockers and corticosteroids. Always inform your doctor about all the medicines you're currently taking.

How should I store my Semi-Daonil Tablets?

Store the medicine at room temperature (below 30°C), protected from light and moisture. Keep it out of reach of children and pets.

What should I do in case of a Semi-Daonil Tablet overdose?

Overdosing can cause severe low blood sugar, which may lead to unconsciousness or seizures. Seek immediate medical attention if this happens.

Certified Content

Written by

Dr Nikita Lobo

Medical Editor & Reviewer | 7 years

BDS, MDS

Reviewed by

Dr. Osama Ahmed

Dental/Medical Writer, Editor, Reviewer | 2 years

Bachelor of Dental Surgery

Check out Editorial Policy

Manufacturer details

Emcure House, T 184, M.I.D.C. Bhosari, Pune 411026

Country of origin: INDIA

References

National Center for Biotechnology Information (2024). PubChem Compound Summary for CID 3488, Glyburide. Retrieved November 14, 2024 from https://pubchem.ncbi.nlm.nih.gov/compound/Glyburide
GLIBENCLAMIDE TABLETS. (n.d.). Retrieved November 14, 2024, from https://rwandafda.gov.rw/wp-content/uploads/2024/02/Glibenclamide%205mg%20tablet-SmPC.pdf
Glynase ® PresTab. (n.d.). https://www.accessdata.fda.gov/drugsatfda_docs/label/2011/020051s017lbl.pdf‌
Diaßeta (glyburide) tablets USP 1.25, 2.5 and 5 mg ... US FDA. (n.d.). https://www.accessdata.fda.gov/drugsatfda_docs/label/2009/017532s030lbl.pdf
Glibenclamide. Glibenclamide - an overview | ScienceDirect Topics. (n.d.). https://www.sciencedirect.com/topics/neuroscience/glibenclamide

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