Brivaracetam
Uses of Brivaracetam
The primary use of Brivaracetam is for managing partial-onset seizures in patients diagnosed with epilepsy. It falls under the category of antiepileptic medicines (AEDs).
It can be used alone or in combination with other seizure medicines to provide an effective seizure management plan.
Side effects of Brivaracetam
Sleepiness or tiredness
Dizziness
Nausea and vomiting
Fever (in children)
Decreased appetite (in children)
How Brivaracetam works
Brivaracetam is an antiepileptic medicine.
It is known to reduce the frequency of seizures by slowing down nerve impulses in the brain that are responsible for causing these seizures. It functions by binding to a protein in the brain known as synaptic vesicle protein 2A (SV2A). When Brivaracetam attaches itself to SV2A, it appears to decrease the release of excitatory neurotransmitters, resulting in reduced stimulation and overactivity of neurons.
Certified content
Written By
Doctor of Medicine
Reviewed By
BMS, FMC, MD Resident
Expert Advice
Dosage Forms Available
Brivaracetam can be taken orally (tablets or oral solution) and intravenously (injection).
Age and Dose Restrictions
The medicine is meant for use in both adults and children aged 1 month and older.
Contraindications
Brivaracetam is contraindicated in people with severe liver problems and a history of depression, mental illness, or suicidal thoughts or behaviour.
Other Medications to Avoid
Brivaracetam can interact with other seizure medications (such as carbamazepine, phenytoin, and primidone), an antibiotic (like rifampin), and herbal supplements (like St. John's wort).
Overdose and Missed Dose
Overdosing on Brivaracetam can cause extreme sleepiness, dizziness, and an inability to wake up. Immediate medical attention should be sought in case of an overdose.
If a dose is missed, it should be taken as soon as remembered unless it is almost time for the next scheduled dose. No extra medicine should be taken to make up for the missed dose.
Management of Side Effects
Most side effects are temporary and generally harmless and resolve when discontinuing this medicine. However, if you experience any severe side effects or worsening of any of the symptoms, please consult your doctor.
Drinking plenty of water can help manage nausea and vomiting.
Rest and relaxation techniques can help manage dizziness.
Eating small meals more frequently can help manage decreased appetite.
Use in Driving and Operating Machinery
Brivaracetam may impair thinking and motor skills. Patients taking this medicine should avoid driving or operating machinery until they know how it affects them.
Use in Pregnancy and Lactation
Brivaracetam may not be safe to use during pregnancy; it should only be used if the benefits outweigh the potential risks. Brivaracetam passes into breast milk and is therefore not recommended for use in breastfeeding mothers. Consult your doctor for more information.
Caution in Other Conditions
The medicine should be used with caution in people with a history of mental illness or suicidal thoughts or behaviour.
For patients with severe liver problems, a lower dose may be needed.
Special Dietary and Lifestyle Recommendations
Regular check-ups are advised to monitor the effect of the medicine and to adjust the dosage if necessary.
Frequently asked questions
Can Brivaracetam cause behavioural changes?
Yes, some people taking Brivaracetam may experience behavioural changes like anxiety, panic attacks, trouble sleeping, and mood swings. These should be reported to a doctor if they occur.
Can Brivaracetam cause weight gain?
No, weight gain is not listed as a common side effect of Brivaracetam. However, everyone's body responds differently to medicines, so if you notice any unusual changes in your body weight, you should consult your doctor.
Does Brivaracetam have any effect on menstruation?
Brivaracetam is not known to affect menstruation. However, if you notice any changes in your menstrual cycle or experience heavy bleeding, you should discuss this with your doctor.
Can Brivaracetam be taken by vegans?
Yes, as far as it is known, there are no animal-derived ingredients in Brivaracetam. However, it is always advisable to check the product label or consult your doctor for more information.
Is there a natural alternative to Brivaracetam?
There is no known natural alternative that can replace the importance of Brivaracetam in managing partial-onset seizures. Always consult your doctor before considering any alternative remedies for epilepsy.
Is Brivaracetam a prescription-only medicine?
Yes, Brivaracetam is a prescription-only medicine that can be obtained only with a valid prescription from a doctor. It is not a controlled substance but should be used strictly under medical supervision.
Is Brivaracetam a steroid?
No, Brivaracetam is not a steroid. It belongs to a group of medicines called antiepileptic medicines (AEDs), which are intended to control and manage seizures in individuals with epilepsy.
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