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Tacrolimus

IMMUNOSUPPRESSANT

Uses of Tacrolimus

Tacrolimus is helpful in the prevention of organ rejection in transplant patients.

Side effects of Tacrolimus

Diarrhoea The Increased Glucose Level In The Blood Increased Thirst Kidney Damage Liver Damage Nausea Stomach Pain

How Tacrolimus works

Tacrolimus falls under the calcineurin inhibitor immunosuppressant agent category. It prevents the activation and proliferation of T-lymphocytes activated by antigens and cytokines such as interleukin IL-3, IL-4, IL-5, GM-CSF, and TNF. It acts by suppressing your body's immunological reaction after an organ transplant (eg. liver, kidney, heart). It benefits the body's acceptance of the new organ.

Certified content

Written By

docImg
Amit SharmaClinical Health & Medical Writer| 3 years

B. Pharm

Reviewed By

Amatul Ameen
Amatul Ameen Clinical Health & Medical Writer| 13 years

B. Pharm, MSc.

Expert Advice

It is recommended Tacrolimus for the prevention of organ rejection in transplant patients. Tacrolimus medicine may require three to four months to start working. You should continue taking Tacrolimus as recommended. Your doctor may recommend routine blood tests to monitor the number of red blood cells in your blood. If you have any unusual symptoms such as bleeding or bruises, a sore throat, mouth ulcers, a high fever, or an overall feeling of sickness, you should consult a doctor. Your doctor may frequently check your kidney function. Drink 8 to 10 glasses of water daily to improve kidney function. Do not stop taking Tacrolimus all of a sudden without first consulting your doctor.

Frequently asked questions

No, it is not safe to take Tacrolimus while pregnant because there is clear evidence that the drug causes a risk to the growing fetus. However, it is used in pregnancy only if the doctor determines its benefits and minimises the risks.

Within 1 to 2 hours, you must experience the benefit of Tacrolimus.

No, it's likely unsafe to take Tacrolimus during breastfeeding. According to limited human data, the medicine may enter the breast milk and harm the unborn baby.

Yes, it should be used with precaution, specifically if you have a history of kidney disorders or problems. Some patients may need a dosage modification of the medicine. If you have any problems, you should consult your doctor.

Yes, it should be used with precaution, specifically if you have a history of liver disorders or problems. Some patients may need a dosage modification of the medicine. If you have any problems, you should consult your doctor.

It is not recommended to use any immunosuppressants (cyclosporin), antibiotics (clotrimazole, voriconazole, erythromycin, clarithromycin, rifampicin), antifungals (fluconazole, itraconazole, ketoconazole), antiemetics (metoclopramide), and anticonvulsants (phenytoin, phenobarbital), antacids medications (lansoprazole, cimetidine, omeprazole), steroid medications (cortisone, prednisolone, methylprednisolone), antivirals medications (aciclovir), antidepressant medications (nefazodone), anticancer medications (imatinib, nilotinib), anti-HIV drugs medications (nelfinavir, saquinavir, ritonavir). Before using any prescription or over-the-counter medications, you must consult your doctor.

Do not use it if you have an allergic reaction (hypersensitivity) to any of its components. Do not take Tacrolimus if you consume St John's wort plant or grapefruit juice and alcohol. Due to a possible interaction, Tacrolimus may increase the chance of serious adverse effects. We recommend that you consult a doctor as soon as possible.

No, please do not stop taking Tacrolimus without first consulting your doctor. There is a chance that symptoms may return if it is suddenly stopped.

No, it is unlikely to affect fertility in either men or women. However, there is currently insufficient evidence to justify any clear conclusion. Consult your doctor for the most accurate information.

No, avoid consuming alcohol while taking Tacrolimus because it could increase dizziness and drowsiness.

Yes, as a possible side effect, Tacrolimus can cause you to suffer a burning sensation. However, you should consult a doctor if the burning sensation worsens.

Yes, using it can cause you to feel nausea and vomiting. If you vomit, drink water or other liquids continuously in small quantities. If you observe symptoms of dehydration, such as persistent vomiting, dark urine with a strong odour, or infrequent urination, consult your doctor. Without first consulting a doctor, avoid taking any additional medications.

Yes, the usage of this medicine may cause a change in colour vision, blurred vision, a narrow vision field, or a problem in focusing. While using Tacrolimus, if you have any visual disturbances, you should consult your doctor immediately. It is recommended that patients take it in combination with regular eye examinations so that the correct dosage may be determined.

Yes, it may cause skin cancer. Therefore, you should try to avoid or minimise prolonged exposure to the sun or artificial light sources like tanning beds. Before going outside in the sunlight, put up protective clothing and apply sunscreen.

Terms & Conditions

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